Wineries, drosophila, alcohol, and Adh

Marks, R. William; Brittnacher, John; McDonald, John F.; Prout, Timothy; Ayala, Francisco J.

doi:10.1007/bf00541790

Cited by 40 publications

(26 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In agreement with three other studies (McKenzie and McKechnie, 1978;Marks et a!., 1980; the data for All Saints show that the distribution of Adh alleles and genotypes in D. melanogaster was homogeneous over all collections, whether taken inside or outside the winery. Contrary results were reported by Briscoe et a!.…”

Section: Discussionsupporting

confidence: 79%

See 1 more Smart Citation

The alcohol dehydrogenase polymorphism of Drosophila melanogaster in relation to environmental ethanol, ethanol tolerance and alcohol dehydrogenase activity

Gibson

Wilks

1988

Heredity

View full text Add to dashboard Cite

Ethanol levels in Drosophila breeding sites were higher in a winery storing fortified wines than in nearby grape pressings or in orchard fruits. The relative abundance of D. simulans to D. melanogaster was negatively correlated with ethanol levels. In D. melanogaster there were no significant differences in AdhF frequency between the orchard and winery populations. The ethanol tolerance of wild caught D. melanogaster males paralleled the levels of ethanol in the breeding sites but Adh alleles and ethanol tolerance segregated largely independently of each other. Levels of ADH activity were positively associated with the ethanol tolerance of the different populations and with levels of ethanol in the breeding sites, but it is argued that the ethanol levels are not causative. Flies from inside the winery had higher ADH levels due mainly to greater amounts of ADH-F. The difference in activity persisted for at least one generation in the laboratory. After ten generations of laboratory culture the differences in ethanol tolerance were still present but there were no significant differences in ADH activity.

show abstract

Section: Discussionsupporting

confidence: 79%

“…Distributions similar to this have been reported before (McKenzie, 1974;Marks et a!., 1980;; however the causative role of ethanol levels has been questioned, and other factors associated with buildings might be involved (David, 1979;Rouault and David, 1982).…”

Section: Discussionsupporting

confidence: 52%

The alcohol dehydrogenase polymorphism of Drosophila melanogaster in relation to environmental ethanol, ethanol tolerance and alcohol dehydrogenase activity

Gibson

Wilks

1988

Heredity

View full text Add to dashboard Cite

show abstract

“…More precisely, a high frequency of F allele would be favoured in wine cellars, while a much lower equilibrium would be favoured in field populations. A higher frequency of Adh-F in wine cellar populations has been observed by various authors in Spain (Briscoe et a!., 1975;Alonso-Moraga et a!., 1985 and Canada (Hickey and McLean, 1980) but not in Australia (McKenzie and Parsons, 1974;McKenzie and McKecknie, 1978) nor in California (Marks et a!., 1980) nor in France (Charles-Palabost et a!., 1985;. There is no general solution to this ecological problem.…”

Section: Resultsmentioning

confidence: 99%

Latitudinal variation of Adh gene frequencies in Drosophila melanogaster: a Mediterranean instability

et al. 1989

View full text Add to dashboard Cite

The relationship between allelic frequencies at the Adh locus and latitude of origin was studied using selected published data from various parts of the world and original observations. An overall increase of Adh-F with increasing latitude was observed but the relationship is not linear. Tropical populations are generally similar, having a low frequency of the F allele (average 15 per cent) and a smooth increase with latitude (one per cent for one degree). Between 30 and 42° latitude, populations living in a Mediterranean climate in various parts of the world (Mediterranean countries, Australia's east coast and North America's west coast) are also similar, with a much higher average frequency of F (70 per cent), a steeper slope (two per cent) and a broader range of variability for a given latitude. In a restricted area (near Cordoba in southern Spain) numerous wild collected samples also showed a large variability, sometimes over a very short distance. Allelic frequencies in Mediterranean countries are thus quite unstable and it is proposed that this phenomenon be called a "Mediterranean instability". Further north, numerous samples from France were characterized by an even higher frequency of F (95 per cent) and a greater homogeneity over a broad geographic area. These observations are discussed and the need for more field studies is emphasized.

show abstract

“…Microgeographic variation in allele frequencies in, and around, wineries (Briscoe eta!., 1975;Hickey and McLean, 1980;Marks et aL, 1980;McKenzie and McKenie, 1981) is not generally related to differences in the ethanol concentrations of the substrates . In terms of macrogeographic variation, David and Bocquet (1975) and Parsons and Stanley (1981) have some evidence that ADH activity and ethanol tolerance are lower in populations 51 close to the equator than in cold temperate regions; this parallels the clinal distribution in F frequency.…”

Section: Introductionmentioning

confidence: 99%

Selective effects of the genetic background and ethanol on the alcohol dehydrogenase polymorphism in Drosophila melanogaster

1984

View full text Add to dashboard Cite

SUMMARYEight freshly caught Australasian mass collections ranging in Adh F frequency from 4 to 96 per cent were each divided into eight selection lines. Two selection lines from each base population were put on one of four types of mediumstandard food supplemented with 0 per cent, 3 per cent, 6 per cent or 9 per cent ethanol. After 30 generations the tolerance of 6 per cent and 9 per cent selection lines on a test dose of 9 per cent ethanol was greater than that of the 0 per cent lines on this dose. The tolerance of the 3 per cent lines on this dose was less than that of the 0 per cent lines. There were no significant differences in the tolerance responses across the eight base populations but in only one did Adh frequencies diverge among the four ethanol selection environments: F frequencies in the Brisbane 9 per cent lines were higher than in the Brisbane 0 per cent, 3 per cent and 6 per cent lines. Although the selection affecting Adh did not generally differ among the four selection environments, it differed highly significantly among the eight base populations. The equilibrium F frequencies predicted from the maximum likelihood estimates of the selection coefficients were in close agreement with the frequencies observed in the original collections. The only aspect of the coefficients which was consistent across base populations was FS heterozygote superiority.

show abstract

Wineries, drosophila, alcohol, and Adh

Cited by 40 publications

References 12 publications

The alcohol dehydrogenase polymorphism of Drosophila melanogaster in relation to environmental ethanol, ethanol tolerance and alcohol dehydrogenase activity

The alcohol dehydrogenase polymorphism of Drosophila melanogaster in relation to environmental ethanol, ethanol tolerance and alcohol dehydrogenase activity

Latitudinal variation of Adh gene frequencies in Drosophila melanogaster: a Mediterranean instability

Selective effects of the genetic background and ethanol on the alcohol dehydrogenase polymorphism in Drosophila melanogaster

Contact Info

Product

Resources

About