“…For example, some publications stem from the same study; there are some contradictions between data and their discussion (e.g., LPS and LPB data in [ 80 ], fatty acid data in [ 81 ], inflammatory markers in [ 82 ], etc. ); and the true clinical relevance of microbiota modification as related to, e.g., circulating lipids ( Table S1 ) [ 83 , 84 , 85 , 86 , 87 , 88 , 89 , 90 , 91 , 92 , 93 , 94 , 95 , 96 , 97 , 98 , 99 , 100 , 101 , 102 , 103 , 104 , 105 , 106 ]. In summary, there is indeed evidence that wine (poly)phenols modulate human physiology, but puffery should be avoided until we can clearly correlate such modifications with undisputable clinical outcomes.…”