Wine, Garlic, and CHD in Seven Countries

Secondary Metabolites in Fruits, Vegetables, Beverages and Other Plant‐based Dietary Components

“…There are very few investigations using raw garlic, arguably because the flavours and smells are so strong that double-blinded, placebo-controlled trials are not possible. There is epidemiological evidence associating reduced risk of colon cancer (Steinmetz et al 1994) and coronary heart disease (Keys 1980) with regular consumption of garlic. Five of six intervention studies using fresh garlic or freshly prepared extracts demonstrated a lowering of serum cholesterol, increased fibrinolytic activity and inhibition of platelet aggregation (Kleijnen et al 1989).…”

Garlic Powder and Plasma Lipids and Lipoproteins

“…There has been some speculation that garlic may play a role in this phenomenon. 11 The availability of relatively odorless garlic tablets and capsules that contain the ingredient believed to be the active substance in reducing cholesterol levels or providing other health benefits makes a randomized, wellcontrolled, double-blind study more feasible than it has been in the past. As noted in our study, only 3 (11%) of 28 patients treated with garlic powder experienced garlic breath or garlic body odor.…”

Olive Leaf Extract and Its Main Component Oleuropein Prevent Chronic Ultraviolet B Radiation-Induced Skin Damage and Carcinogenesis in Hairless Mice

“…Thus, there has been great interest in the use of dietary supplements in the form of complementary and alternative medicines derived from naturally occurring botanicals for the prevention of UV irradiation-induced photodamage including skin cancer. The Mediterranean diet, rich in fruits, vegetables, and fish, has been associated with a lower incidence of diseases and an overall improvement in health (5)(6)(7)(8). These findings were attributed to the high consumption of olive oil and olive leaf (Olea europaea L. Oleaceae).…”