Abstract:In the last 2 decades, important advances in the treatment of Wilms' tumor have been made. The remarkable improvement in survival in these patients has been the product of new surgical techniques, classification of the tumors into prognostic stages upon initial presentation and the tailoring of chemotherapy and radiation therapy thus permitted. A brief historical perspective is presented with a review of the current treatment and ongoing studies.
“…also noted similar features . According to other studies done outside of Latin America, the frequency of hypertension ranges from 25% to 63% . WT secretes renin or there is extrinsic compression of the tumor on the renal artery, with triggering of the renin–angiotensin system .…”
Section: Discussionmentioning
confidence: 97%
“…12 According to other studies done outside of Latin America, the frequency of hypertension ranges from 25% to 63%. 22,23 WT secretes renin or there is extrinsic compression of the tumor on the renal artery, with triggering of the reninangiotensin system. 24 Hematological abnormalities, such as coagulation disorder, were observed in one of the present patients (2.2%) and were described only in the Mexican study by Hernández-Cruz et al 8 Only five Latin American studies described congenital anomalies associated with WT.…”
Death is closely related to late diagnosis in WT. Oncologic services should also be concerned about morbidity caused by therapeutic options in cases of late diagnosis, and the consequences for quality of life.
“…also noted similar features . According to other studies done outside of Latin America, the frequency of hypertension ranges from 25% to 63% . WT secretes renin or there is extrinsic compression of the tumor on the renal artery, with triggering of the renin–angiotensin system .…”
Section: Discussionmentioning
confidence: 97%
“…12 According to other studies done outside of Latin America, the frequency of hypertension ranges from 25% to 63%. 22,23 WT secretes renin or there is extrinsic compression of the tumor on the renal artery, with triggering of the reninangiotensin system. 24 Hematological abnormalities, such as coagulation disorder, were observed in one of the present patients (2.2%) and were described only in the Mexican study by Hernández-Cruz et al 8 Only five Latin American studies described congenital anomalies associated with WT.…”
Death is closely related to late diagnosis in WT. Oncologic services should also be concerned about morbidity caused by therapeutic options in cases of late diagnosis, and the consequences for quality of life.
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