Wilhelm Ebstein and the History of Surgery for Ebstein's Disease

Robicsek, Francis

doi:10.1055/s-0032-1304540

Cited by 4 publications

(3 citation statements)

References 27 publications

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“…In Ebstein's anomaly, the anterior leaflet of tricuspid valve enlarges, the parietal leaflet and posterior leaflet move down, and the tricuspid valve is attached to the right ventricular wall, leading to right atrial enlargement. [11,12] During fetal period, increased right atrial pressure caused by acleistocardia and severe tricuspid valve regurgitation leads to right-to-left shunt. In early stage after birth, the infants have cyanosis due to right-to-left shunt.…”

Section: Discussionmentioning

confidence: 99%

Investigating the characteristics of echocardiogram, surgical treatment, chromosome and prognosis for fetal right heart enlargement

et al. 2018

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The prognosis of right heart enlargement varies according to different etiologies. The purpose of this study was to investigate the characteristics of echocardiogram, surgical treatment, chromosome and prognosis for fetal right heart enlargement.The foetal echocardiogram was performed on 3987 pregnant women, and then 88 fetuses with right heart enlargement were identified. The data about prenatal and postnatal echocardiograms, postnatal cardiac surgical treatment, karyotype analysis and autopsy after induced labor were analyzed in the 88 fetuses.Except the 1111 cases that had loss of follow-up, 2876 cases had complete data. Among the 2876 cases, right heart enlargement was identified in 88 fetuses. Of the 88 fetuses, 15 had total atrioventricular septal defect (unbalanced type: right ventricular dominance), 15 Ebstein's anomaly, 18 fallot tetrad, 14 double outlet right ventricle, 13 total anomalous pulmonary venous drainage, and 13 premature closure of ductus arteriosus. Chromosomal abnormality was found in 12 cases.There are many etiological factors causing right heart enlargement. The prognosis is better in the fetuses with single heart malformation than in the fetuses who have extracardiac malformation or/and chromosomal abnormality besides heart malformation. Fetal echocardiography combined with karyotype analysis can provide important bases for evaluating the prognosis of fetuses with right heart enlargement.

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Section: Discussionmentioning

confidence: 99%

Investigating the characteristics of echocardiogram, surgical treatment, chromosome and prognosis for fetal right heart enlargement

et al. 2018

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“…EA [ 1 ] is a rare and complex congenital cardiac malformation, [ 2 , 3 ] which was initially founded by Breslaus doctor Wilhelm Ebstein in 1866 when he did the heart autopsy. EA accounts for 0.5% to 1% of all congenital cardiac disease, [ 4 – 7 ] and only 5% of patients survive beyond the fifth decade.…”

Section: Discussionmentioning

confidence: 99%

Acute arterial embolism of left lower extremity caused by paradoxical embolism in Ebstein's anomaly

Ma²,

Yan³

et al. 2017

Medicine

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Introduction:Ebstein's anomaly is a benign and stable congenital heart disease for asymptomatic patients. Despite a low incidence of Ebstein's anomaly (EA), patients’ quality of life can be badly affected by EA without positive surgical intervention. Especially EA is associated with other congenital heart disease, such as the atrial septal defect, patent foramen ovale, and arterial embolism exclude other reasons, it is often considered to be the consequence of paradoxical embolism, and surgical intervention must be conducted.Case report:An 11-year-old girl falling off the bed suffered pain from left lower extremity. Echocardiographic evaluation revealed an EA, severe tricuspid regurgitation, and secundum atrial septal defect. Both left leg amputation and cardiac surgery were conducted after recovery. Under the condition of anesthesia cardiopulmonary bypass extracorporeal circulation, atrial septal defect repair and Cone reconstruction of the tricuspid valve were performed. Patient recovered well and left hospital smoothly.Discussion:EA is a rare and complex congenital cardiac malformation. There are about 80% to 90% of EA patients with combined atrial septal defect and patent foramen ovale. Sudden arterial occlusion is very rare especially in childhood. When thoracic roentgenoscopy, arterial blood gas analysis, coagulation test, and echocardiographic of lower extremity deep venous system are all normal, one should consider the possibility of a paradoxical embolism. If patients have the paradoxical embolism or worsening tricuspid regurgitation, the most suitable therapeutic regimen should be chosen according to patients’ condition. With surgical techniques and methods renewed continuously, cone reconstruction of the tricuspid valve has been confirmed in clinical trials, which can use its own tissues to form not only central bloodstream, but also the coaption between leaflet and leaflet.

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“…The significant apical displacement of the part of the tricuspid valve, also called Ebstein's anomaly (EA), [1] is a rare and complex congenital cardiac malformation which was initially founded by Breslaus doctor Wilhelm Ebstein in 1866 when he did the heart autopsy. [2,3] EA accounts for 0.5% to 1% of all congenital cardiac disease [4–6] and only 5% of patients survive beyond the fifth decade.…”

Section: Introductionmentioning

confidence: 99%

The modified cone reconstruction in the treatment of Ebstein's anomaly

Chen

Ma³

et al. 2017

Medicine

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Wilhelm Ebstein and the History of Surgery for Ebstein's Disease

Abstract: In the mirror of the life-story of Wilhelm Ebstein, the discovery of "Ebstein's Disease" is presented. The readers are guided through the individual stages of the development of surgical treatment of the condition.

Cited by 4 publications

References 27 publications

Investigating the characteristics of echocardiogram, surgical treatment, chromosome and prognosis for fetal right heart enlargement

Investigating the characteristics of echocardiogram, surgical treatment, chromosome and prognosis for fetal right heart enlargement

Acute arterial embolism of left lower extremity caused by paradoxical embolism in Ebstein's anomaly

The modified cone reconstruction in the treatment of Ebstein's anomaly

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