Wild garlic extract reduces lipid peroxidation in terbuthylazine-treated human erythrocytes

Davidović-Plavšić, Biljana; Kukavica, Biljana; Škondrić, Siniša; Jiménez-Gallardo, Carlos; Žabić, Mirjana

doi:10.1080/1354750x.2021.1953598

Cited by 4 publications

(2 citation statements)

References 60 publications

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“…In addition, mitigating lipid peroxidation, which is a common benefit role among nutrients, functional foods and medicinal plants (Akbari‐Fakhrabadi, Heshmati, Sepidarkish, & Shidfar, 2018; Heshmati et al, 2019; Loloei et al, 2019) is a another garlic favorable impact on lipid profile. It has been proposed that garlic can decrease stress oxidative and prevent lipid peroxidation by scavenging superoxide radicals, free radicals of iron, and reactive oxygen species either by enhancing oxidative defense system such as glutathione peroxidase or through its phenolic components (Das & Saha, 2009; Davidović‐Plavšić, Kukavica, Škondrić, Jimenez‐Gallardo, & Žabić, 2021; Nuutila, Puupponen‐Pimiä, Aarni, & Oksman‐Caldentey, 2003).…”

Section: Discussionmentioning

confidence: 99%

The effect of garlic (Allium sativum) supplementation on the lipid parameters and blood pressure levels in women with polycystic ovary syndrome: A randomized controlled trial

Zadhoush

Alavi-Naeini

Feizi

et al. 2021

Phytotherapy Research

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Polycystic ovary syndrome (PCOS) is the most prevalent female endocrine-related disorder in reproductive ages. The aim of the study was to investigate the effect of garlic on the lipid parameters and blood pressure levels in women with PCOS. The present study was a randomized, double-blinded control trial, conducted on 80 PCOS patients. Participants were taught to intake either a total 800 mg/day garlic supplement or an identical placebo (starch) after lunch for 8 weeks. Physical activity, diet intake, anthropometric measures, and blood pressure were evaluated at baseline and end of the study. The blood sample was also taken to assess the change in outcomes of interest at the pre-and post-intervention. Garlic supplementation significantly reduced serum total cholesterol (change mean difference: À8.05, 95% CI: À15.47, À0.62) and LDL-C (change mean difference: À7.67, 95%CI: À14.64, À0.70) levels in comparison to the control group. In addition, a trend to a significant decrease was found in serum triglyceride levels and Systolic blood pressure; however, no significant difference was observed between two groups in HDL-C and diastolic blood pressure levels. The present study suggested that garlic supplementation might be effective on lipid markers improvement. Further studies are needed to confirm our findings.

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Section: Discussionmentioning

confidence: 99%

The effect of garlic (Allium sativum) supplementation on the lipid parameters and blood pressure levels in women with polycystic ovary syndrome: A randomized controlled trial

Zadhoush

Alavi-Naeini

Feizi

et al. 2021

Phytotherapy Research

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“…In vertebrates, erythrocytes (red blood cells) transfer oxygen from the lungs or gills to body tissues via the circulatory system (Karabulut et al 2009). The structure of erythrocyte membrane is composed of a phospholipid bilayer and imbedded proteins, and the membrane is the direct target of lipid oxidation (Davidovic-Plavsic et al 2021). The importance of erythrocyte as a model for lipid oxidation study is due to the fact that residual blood can promote lipid oxidation upon hemolysis and release of Hb (Richards and Hultin 2002).…”

Section: Erythrocytesmentioning

confidence: 99%

Model systems for studying lipid oxidation associated with muscle foods: Methods, challenges, and prospects

Tatiyaborworntham

Hajimohammadi

et al. 2022

Critical Reviews in Food Science and Nutrition

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Lipid oxidation is a complex process in muscle-based foods (red meat, poultry and fish) causing severe quality deterioration, e.g., off-odors, discoloration, texture defects and nutritional loss. The complexity of muscle tissue -both composition and structure-poses as a formidable challenge in directly clarifying the mechanisms of lipid oxidation in muscle-based foods. Therefore, different in vitro model systems simulating different aspects of muscle have been used to study the pathways of lipid oxidation. in this review, we discuss the principle, preparation, implementation as well as advantages and disadvantages of seven commonly-studied model systems that mimic either compositional or structural aspects of actual meat: emulsions, fatty acid micelles, liposomes, microsomes, erythrocytes, washed muscle mince, and muscle homogenates. Furthermore, we evaluate the prospects of stem cells, tissue cultures and three-dimensional printing for future model system development. Based on this reviewing of oxidation models, tailoring correct model to different study aims could be facilitated, and readers are becoming acquainted with advantages and shortcomings. in addition, insight into recent technology developments, e.g., stem cell-and tissue-cultures as well as three-dimensional printing could provide new opportunities to overcome the current bottlenecks of lipid oxidation studies in muscle.

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Antioxidant and Antithrombotic Activities of Kenaf Seed (Hibiscus cannabinus) Coat Ethanol Extract in Sprague Dawley Rats

Hanumegowda

Srinivasa

Shivaiah

et al. 2022

Appl Biochem Biotechnol

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Wild garlic extract reduces lipid peroxidation in terbuthylazine-treated human erythrocytes

Cited by 4 publications

References 60 publications

The effect of garlic (Allium sativum) supplementation on the lipid parameters and blood pressure levels in women with polycystic ovary syndrome: A randomized controlled trial

The effect of garlic (Allium sativum) supplementation on the lipid parameters and blood pressure levels in women with polycystic ovary syndrome: A randomized controlled trial

Model systems for studying lipid oxidation associated with muscle foods: Methods, challenges, and prospects

Antioxidant and Antithrombotic Activities of Kenaf Seed (Hibiscus cannabinus) Coat Ethanol Extract in Sprague Dawley Rats

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