Wiesner nevus

Clinicopathologically problematic melanocytic tumors: a case-based review

“…Based on these findings, it was suggested that biallelic inactivation of BAP1 is related to a clinically and morphologically distinct type of melanocytic neoplasm [ 23 ]. The latter was further reported in subsequent publications, describing sporadic cases of BAPoma, displaying identical clinical and histopathological characteristics [ 24 – 27 ].…”

“…Clinically, these tumors develop as slowly growing pink nodules, not suggestive of a specific diagnosis. On the other hand, the dermoscopic pattern of this entity is scantily described in the literature and seems to differ significantly from a banal dermal nevus [ 24 ]. For example, in our patient, the in-focus arborizing vessels in dermoscopy strongly suggested a basal cell carcinoma.…”

“…However, these lesions had clinical and histopathological characteristics similar to those presented by Wiesner et al [ 23 ] as benign tumors. Better understanding of their biology will enhance our ability to distinguish them from other melanocytic neoplasms and better classify them in the future [ 24 ].…”