“…During the follow-up period (the length of which is not clear), four patients had residual BE islands, one of which was underneath the newly formed squamous epithelium, and 27 % had strictures [53]. Various new techniques for larger-area mucosectomy were presented in animal experiments, such as a modified needle-knife method [54], the application of a holmium laser [55], pressurized CO 2 gas [56], cryotherapy [57] and radiofrequency [58].…”