2018
DOI: 10.5312/wjo.v9.i4.60
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Why total knees fail-A modern perspective review

Abstract: Historically, the most common mechanism of total knee arthroplasty (TKA) failures included aseptic loosening, instability and malalignment. As polyethylene production improved, modes of failure from polyethylene wear and subsequent osteolysis became less prevalent. Newer longitudinal studies report that infection has become the primary acute cause of failure with loosening and instability remaining as the overall greatest reasons for revision. Clinical database and worldwide national registries confirm these r… Show more

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Cited by 79 publications
(64 citation statements)
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“…Aseptic loosening is one of the most common complications of surgical joint replacement [19]. It is a chronic and continuous pathological process accompanied by in ltration of in ammatory cells [20].…”
Section: Discussionmentioning
confidence: 99%
“…Aseptic loosening is one of the most common complications of surgical joint replacement [19]. It is a chronic and continuous pathological process accompanied by in ltration of in ammatory cells [20].…”
Section: Discussionmentioning
confidence: 99%
“…Polyethylene wear is no longer the most common indication for late revision surgery, due to improved polyethylene production. [66][67][68] Improvements in polyethylene liner durability include highly cross-linked, ultra-high-molecular-weight polyethylene, treatment of the polyethylene with vitamin E, limiting polyethylene shelf life, and avoidance of gamma radiation of polyethylene liners in air that increases cross linking but also produces free radicals that in the presence of oxygen promotes degradation of the liner. 69 Malalignment and instability can accelerate polyethylene wear.…”
Section: Polyethylene Wearmentioning
confidence: 99%
“…Tarihsel süreç içerisinde TDP sonrasında ağrı ve başarısızlık nedenleri; aseptik gevşeme, instabilite ve dizilim bozukluğu olarak belirtilmiştir. [19] Polietilen teknolojisindeki gelişmeler, polietilen aşınması ve buna bağlı osteoliz gelişme oranını çok azaltmıştır; günümüzde enfeksiyon, gevşeme ve instabilite en çok görülen revizyon nedenleridir. [19] Ağrının nedeni ortaya konulduktan sonra, tedavi cerrah için kolay olacaktır.…”
Section: Görüntülemeunclassified
“…[19] Polietilen teknolojisindeki gelişmeler, polietilen aşınması ve buna bağlı osteoliz gelişme oranını çok azaltmıştır; günümüzde enfeksiyon, gevşeme ve instabilite en çok görülen revizyon nedenleridir. [19] Ağrının nedeni ortaya konulduktan sonra, tedavi cerrah için kolay olacaktır. Ağrılı bir TDP'de temel prensip, ağrının nedeni ortaya konulmadan revizyon gibi majör bir cerrahinin yapılmasına karar verilmemesi gerektiğidir.…”
Section: Görüntülemeunclassified