2006
DOI: 10.1038/nbt1206-1472
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Why the omega-3 piggy should not go to market

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Cited by 11 publications
(4 citation statements)
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“…Only plants that express the selected marker gene and carry the transgene of interest will survive; and 6) Regeneration of complete plants in a series of selective media providing nutrients under controlled environmental conditions (a process that is known as TC) [38] . This process is most commonly used to develop insect resistant crops, which are referred to as GM organisms (GMOs) [39] .…”
Section: Production Of Gm Cropsmentioning
confidence: 99%
“…Only plants that express the selected marker gene and carry the transgene of interest will survive; and 6) Regeneration of complete plants in a series of selective media providing nutrients under controlled environmental conditions (a process that is known as TC) [38] . This process is most commonly used to develop insect resistant crops, which are referred to as GM organisms (GMOs) [39] .…”
Section: Production Of Gm Cropsmentioning
confidence: 99%
“…Furthermore, related modifications have been observed in pigs containing the C. elegans n–3 fatty acid desaturase gene (encoded by the fat-1 gene) [ 101 , 102 , 103 ]. Similar findings were obtained when CRISPR/Cas9 was used to insert the fat-1 gene into the pig in the rosa 26 locus [ 104 ].…”
Section: Genome Editing In Ruminants Such As Cattle and Buffalosmentioning
confidence: 99%
“…For example, Lai and colleagues generated cloned pigs that expressed the fat-1 gene from the nematode Caenorhabditis elegans and that exhibited significantly reduced ratios of n-6 to n-3 fatty acids, which might have human health benefits [ 39 ]. Although some have questioned the value of such pigs [ 40 ], nevertheless others have also generated pigs carrying the C. elegans fat-1 gene (which encodes an n-3 fatty acid desaturase) and have observed similar changes [ 41 , 42 ], including Li and colleagues, who used ‘clustered regularly interspaced short palindromic repeats’ (CRISPR)–CRISPR-associated 9 (Cas9) gene-editing technology for the directed integration of the fat-1 gene from C. elegans into the porcine Rosa 26 locus [ 43 ].…”
Section: Examples Of Genetic Modificationmentioning
confidence: 99%