Why obesity, hypertension, diabetes, and ethnicities are common risk factors for COVID‐19 and H1N1 influenza infections

Miyazawa, Daisuke

doi:10.1002/jmv.26220

Cited by 20 publications

(18 citation statements)

References 10 publications

(7 reference statements)

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“…This mechanism underlies the development of DM in SARS-CoV patients. 6 Besides this, the aberrant immunity caused by 7,8 Several reasons may underlie this unexpected finding. First, the duration of DM may be more important than the presence of DM itself.…”

Section: Discussionmentioning

confidence: 97%

Newly diagnosed diabetes mellitus, DKA, and COVID‐19: Causality or coincidence? A report of three cases

Suwanwongse

Shabarek

2020

Journal of Medical Virology

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Novel coronavirus disease 2019 (COVID‐19), a 2020 pandemic, has resulted in an unexpected loss of lives, quality of life, and economy. The COVID‐19 clinical spectrum varies from asymptomatic to death, and its complications may involve various organs. Notwithstanding, the impact of COVID‐19 on endocrine systems is understudied. Previous coronavirus outbreak such as SARS‐CoV can cause new‐onset diabetes mellitus (DM). However, there were only two previous case reports on newly diagnosed DM in COVID‐19 patients. Here, we described three patients who had newly diagnosed DM associated with COVID‐19. COVID‐19 likely unmasked existing DM by aggravating its metabolic complications rather than causing the new‐onset DM in these patients. However, more research is needed to evaluate if there is a casualty relationship between the development of DM, DKA, and COVID‐19. This article is protected by copyright. All rights reserved.

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Section: Discussionmentioning

confidence: 97%

Newly diagnosed diabetes mellitus, DKA, and COVID‐19: Causality or coincidence? A report of three cases

Suwanwongse

Shabarek

2020

Journal of Medical Virology

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“…All cases of new-onset DM in COVID-19 mentioned in the literature so far were associated with good outcomes. On the contrary, it is known that pre-existing DM and COVID-19 have a negative bidirectional relationship with unfavorable outcomes [ 15 , 18 ]. This could be related to the short duration of the newly diagnosed disease in case reports; moreover, the poor outcomes of patients previously diagnosed with DM in larger studies could be due to co-morbid conditions and preexisting disease complications.…”

Section: Discussionmentioning

confidence: 99%

New-Onset Diabetes Mellitus Presenting As Diabetic Ketoacidosis in Patients With COVID-19: A Case Series

Sarwani¹,

Saeed²,

Husain³

et al. 2021

Cureus

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Coronavirus disease 2019 , a 2020 pandemic, has been linked to another global health problem, the diabetes pandemic. Both are existing in a bi-directional association. COVID-19 has been shown to be associated with worse outcomes in those with pre-existing diabetes mellitus. Nevertheless, recent data have emerged highlighting the inter-relationship between new-onset diabetes mellitus and COVID-19. Here, we present four cases admitted to the hospital with newly diagnosed diabetes mellitus associated with COVID-19. We aim to review the available literature regarding the complex association between COVID-19 and newonset diabetes, causative factors and triggers, treatment strategies, outcomes, and its burden on the health system in general.

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“…ACC, AHA and Heart Failure Society of America (HFSA) [49] admits "but there are no experimental or clinical data demonstrating beneficial or adverse outcomes among COVID-19 patients using ACE-I or ARB medications." Quite a few studies have been doing for these subjects [50]- [69].…”

Section: Introductionmentioning

confidence: 99%

An Analysis of Blood Pressure Situations in Japan Using the Large-Scale Medical Checkup Dataset

Nawata¹

2021

Health

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Background: The high blood pressure (BP) or hypertension is a widely prevalent disease and its costs are very high, and many studies about the relationships between BP and health conditions have been done. We need to know the precise distributions of BP and factors affecting BP. Data and Methods: The distributions of BP are analyzed using 12,877,653 observations obtained from the JMDC Claims Database. The factors that may affect the BP are analyzed by the regression models using 4,615,346 observations. Results: The averages of systolic BP (SBP) and diastolic BP (DBP) are 120.4 and 74.2 mmHg with standard deviations of 15.9 and 11.3 mmHg, respectively. Among the nonmodifiable factors, age and gender are important factors. Among the modifiable factors, variables related to obesity are important risk factors. Taking antihypertensive drugs makes SBP and DBP 13.4 mmHg and 7.8 mmHg lower. Conclusion: The criteria of BP should be carefully determined considering age and gender. The effects of age may be a little different for SBP and DBP. It is necessary to use the proper model to evaluate the effect of antihypertensive drugs correctly. Limitations: The dataset is observatory. Although there are various types of treatment methods and antihypertension drugs, their effects are not evaluated.

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Why obesity, hypertension, diabetes, and ethnicities are common risk factors for COVID‐19 and H1N1 influenza infections

Cited by 20 publications

References 10 publications

Newly diagnosed diabetes mellitus, DKA, and COVID‐19: Causality or coincidence? A report of three cases

Newly diagnosed diabetes mellitus, DKA, and COVID‐19: Causality or coincidence? A report of three cases

New-Onset Diabetes Mellitus Presenting As Diabetic Ketoacidosis in Patients With COVID-19: A Case Series

An Analysis of Blood Pressure Situations in Japan Using the Large-Scale Medical Checkup Dataset

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