Why don’t cancer patients enter clinical trials? A review

Promoting clinical research to medically underserved communities: Current practices and perceptions about clinical trial recruiting strategies

“…Patient-related barriers include cognitive barriers, such as lack of awareness or understanding about CTs [13], structural barriers, which include concerns about participation costs, travel and insurance coverage [14], and psychological barriers, including misperceptions, distrust, and fear [15]. Physician-related barriers include limited knowledge of ongoing CTs, unsupportive attitudes, and a lack of motivation to enroll patients [16,17].…”

Follow-up care for young adult survivors of cancer: lessons from pediatrics

“…Although efforts are being made to increase the number of adult cancer patients entered into clinical trials, only around 10% of eligible patients are accrued [74]. Barriers to recruitment include attitudes of some doctors toward clinical trials [20] and patient concerns with the research process and its implications [71]. Superior survival in children has also been attributed to the fact that they are more resilient than adults and can tolerate more aggressive therapy.…”

From information processing to behavioral intentions: Exploring cancer patients’ motivations for clinical trial enrollment

“…Operating under the assumption that the mass media convey most risk information to the public, it incorporates ideas that describe how the audiences select media channels to gratify their varying needs [41]. In the context of clinical trial communication, however, most people still rely on their doctors as primary source of information [4,8,42]. Therefore, this component of the RISP model warrants some conceptual adaptation.…”