Why do foot ulcers recur in diabetic patients?

Mantey, I.; Foster, Ali; Spencer, Sue; Edmonds, M E

doi:10.1046/j.1464-5491.1999.00032.x

Cited by 85 publications

(74 citation statements)

References 22 publications

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“…CONCLUSIONS -Recurrent foot ulceration is a major health problem in diabetic patients (2)(3)(4). During 2-year follow-up, 39% of our patients had recurrent ulcers for which treatment with a TCC was indicated.…”

Section: Research Design Andmentioning

confidence: 78%

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Casting of Recurrent Diabetic Foot Ulcers

et al. 2005

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Section: Research Design Andmentioning

confidence: 78%

“…Unfortunately, many ulcers recur (2), and recurrence rates up to 70% have been reported (3)(4)(5). Little information is available on the management and outcome of these ulcers.…”

mentioning

confidence: 99%

Casting of Recurrent Diabetic Foot Ulcers

et al. 2005

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“…Chronic hyperglycemia, which develops as a result of poor glycemic control, is known to cause impairment in neutrophil functions and to provide a basis for infections [15,16]. High levels of HbA1c were suggested in two different studies to pave the way for the recurrence of diabetic foot infections and the development of neuropathy, and as a result, become a risk factor for amputation [17,18]. Mean HbA1c levels in the present study at the beginning were 8.17% and high values were detected in patients with a prior history of diabetic foot infection.…”

Section: Discussionmentioning

confidence: 99%

Diabetic foot infections: effective microorganisms and factors affecting the frequency of osteomyelitis and amputation

Sönmezer¹,

Tülek²,

Ozsoy³

et al. 2015

Eur Res J

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Diabetic foot infection is one of the complications of diabetes; it has high mortality and morbidity and is also one of the most common causes of hospitalization in diabetes [1,2]. Diabetic foot infections generally start as a soft tissue infection secondary to a minor trauma, may advance to osteomyelitis, and eventually become a risk factor for amputation [3,4]. Approximately one-fourth of ABSTRACT 119Objectives. Diabetic foot infections are common reason for hospitalization and are associated with high morbidity and mortality. We aimed to evaluate the clinic features and predisposed causes of osteomyelitis and amputation of patients with diabetic foot infections. Methods. Patients with diabetic foot infections who admitted and hospitalized at Infection Diseases and Clinical Microbiology department between January 2012 and July 2014 were included. Osteomyelitis was evaluated using magnetic resonance imaging (MRI) or bone scintigraphy. Microbiological examinations (Gram staining and culture) of the debridement materials and pus aspiration materials of the lesions were performed. Results. Of the seventy-three diabetic foot infected patients, 37 (50.7%) were female, and 36 (49.3%) were male. The mean age of patients was 57±9.8 years. The mean duration of diabetes and HbA1c level were 13.3±5.3 years and 8.17±1.83%; respectively. Soft tissue infection without osteomyelitis was present in only 34 out of 73 (46.5%) patients. A total of 89 pathogens were identified in 52 patients whereas any microorganism was not identified in 28.7%. Polymicrobial infections were detected in 30 (41%) patients. The most common isolated microorganism was Pseudomonas aeruginosa (36.9%), followed by Staphylococcus aureus (31.5%) and Enterococcus spp. (13.6%). Of the 37 (50.7%) patients had a history of diabetic foot infection previously, osteomyelitis progression was higher (89.2%) and statistically significant in these patients. Twelve (16.4%) patients underwent amputation. Conclusions. Advanced age and presence of osteomyelitis were found as risk factors for amputation. In the presence of osteomyelitis, treatment of diabetic foot infections is difficult and amputation rate is higher. For this reason, diabetic foot infections should be promptly treated before the development of osteomyelitis, and multidisciplinary approach is needed.

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“…The patients socks should be made from cotton and be seam-free. They also should be warned against smoking to avoid worsening blood circulation [62] .…”

Section: Electrotherapy Methodsmentioning

confidence: 99%

Does physical therapy and rehabilitation improve outcomes for diabetic foot ulcers?

Turan

Ertuğrul

Lipsky

et al. 2015

WJEM

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One of the most common and serious complications of diabetes mellitus is ulceration of the foot. Among persons with diabetes, 12%-25% will present to a healthcare institution for a foot disorder during their lifespan. Despite currently available medical and surgical treatments, these are still the most common diabetes-related cause of hospitalization and of lower extremity amputations. Thus, many adjunctive and complementary treatments have been developed in an attempt to improve outcomes. We herein review the available literature on the effectiveness of several treatments, including superficial and deep heaters, electro-therapy procedures, prophylactic methods, exercise and shoe modifications, on diabetic foot wounds. Overall, although physical therapy modalities seem to be useful in the treatment of diabetic foot wounds, further randomized clinical studies are required.

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Why do foot ulcers recur in diabetic patients?

Abstract: Patients who develop recurrent foot ulceration delay in reporting symptoms, when compared with diabetic patients whose foot ulceration does not recur. The relapsers also have evidence of poorer glycaemic control, more neuropathy and increased alcohol intake.

Cited by 85 publications

References 22 publications

Casting of Recurrent Diabetic Foot Ulcers

Casting of Recurrent Diabetic Foot Ulcers

Diabetic foot infections: effective microorganisms and factors affecting the frequency of osteomyelitis and amputation

Does physical therapy and rehabilitation improve outcomes for diabetic foot ulcers?

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