Why ammonium detection is particularly challenging but insightful with ionophore-based potentiometric sensors – an overview of the progress in the last 20 years

Cuartero, María; Colozza, Noemi; Fernández-Pérez, B.M.; Crespo, Gastón A.

doi:10.1039/d0an00327a

Cited by 51 publications

(50 citation statements)

References 100 publications

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“…Historically, measurements with ISEs were done at an open circuit potential, but over the last few decades, the application was extended by applying an external current or potential control [79]. These tools are investigated in the detection of a large variety of contaminants such as ammonium [80], copper sulfate [81] and heavy metals [82].…”

Section: Comparison Of Electrochemical Techniquesmentioning

confidence: 99%

Towards Clean and Safe Water: A Review on the Emerging Role of Imprinted Polymer-Based Electrochemical Sensors

Zheng

Khaoulani

Ktari³

et al. 2021

Sensors

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This review critically summarizes the knowledge of imprinted polymer-based electrochemical sensors for the detection of pesticides, metal ions and waterborne pathogenic bacteria, focusing on the last five years. MIP-based electrochemical sensors exhibit low limits of detection (LOD), high selectivity, high sensitivity and low cost. We put the emphasis on the design of imprinted polymers and their composites and coatings by radical polymerization, oxidative polymerization of conjugated monomers or sol-gel chemistry. Whilst most imprinted polymers are used in conjunction with differential pulse or square wave voltammetry for sensing organics and metal ions, electrochemical impedance spectroscopy (EIS) appears as the chief technique for detecting bacteria or their corresponding proteins. Interestingly, bacteria could also be probed via their quorum sensing signaling molecules or flagella proteins. If much has been developed in the past decade with glassy carbon or gold electrodes, it is clear that carbon paste electrodes of imprinted polymers are more and more investigated due to their versatility. Shortlisted case studies were critically reviewed and discussed; clearly, a plethora of tricky strategies of designing selective electrochemical sensors are offered to “Imprinters”. We anticipate that this review will be of interest to experts and newcomers in the field who are paying time and effort combining electrochemical sensors with MIP technology.

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Section: Comparison Of Electrochemical Techniquesmentioning

confidence: 99%

Towards Clean and Safe Water: A Review on the Emerging Role of Imprinted Polymer-Based Electrochemical Sensors

Zheng

Khaoulani

Ktari³

et al. 2021

Sensors

View full text Add to dashboard Cite

show abstract

“…In addition to the solid contact used, the electrochemical performance of the ammonium-selective solid-state electrode is also highly dependent on the composition of the membrane and substrate employed in the sensor design. In terms of detection mechanism, ionophore-based potentiometric sensors with a polyvinyl chloride (PVC) membrane are the most commonly used ammonium sensor class [17].…”

Section: Introductionmentioning

confidence: 99%

Fabrication of an All-Solid-State Ammonium Paper Electrode Using a Graphite-Polyvinyl Butyral Transducer Layer

et al. 2021

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A planar solid-state ammonium-selective electrode, employing a composite mediator layer of graphite particles embedded in a polyvinyl butyral matrix on top of an inkjet-printed silver electrode, is presented in this paper. The effect of graphite powder mass fraction on the magnitude of the potentiometric response of the sensor was systematically verified using a batch-mode and a flow injection measurement setup. Under steady-state conditions, the paper electrode provided a Nernstian response of 57.30 mV/pNH4 over the concentration range of 10−5 M to 10−1 M with a detection limit of 4.8 × 10−6 M, while the analytical performance of the array in flow mode showed a narrower linear range (10−4 M to 10−1 M; 60.91 mV/pNH4 slope) with a LOD value of 5.6 × 10−5 M. The experimental results indicate that the prepared electrode exhibited high stability and fast response to different molar concentrations of ammonium chloride solutions. The pH-response of the paper NH4-ISE was also investigated, and the sensor remained stable in the pH range of 2.5–8.5. The potentiometric sensor presented here is simple, lightweight and inexpensive, with a potential application for in-situ analysis of environmental water samples.

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“…In this context, understanding and controlling the metabolism of these neurotransmitters by monoaminoxidase enzymes [26][27][28][29][30] allows the treatment of various types of mental and neurodegenerative disorders. [31,32] The binding or recognition of a molecule that contains an ammonium group constitutes a subtle balance of all the interactions between host and guest [33][34][35][36][37][38][39] where the establishment of hydrogen bonds is often crucial. [40][41][42][43][44] In other cases, depending on the characteristics of the biochemical process and the species involved, a proton transfer from the ammonium cation to other functionality takes place.…”

Section: Introductionmentioning

confidence: 99%

“…N-sp 2 organobases The organobase family with an interacting N-sp 2 atom was split into five categories: azoles (13)(14)(15)(16)(17)(18)(19)(20)(21)(22); azines (23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35)(36); amidines (37)(38)(39)(40)(41)(42)(43); guanidines (44)(45)(46)(47)(48) and azapolycycles (49)(50)(51)(52)(53)(54)(55)(56)(57)(58)(59)(60)(61). We start commenting the selected azoles and azines (Figure 5).…”

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confidence: 99%

Alkylammonium Cation Affinities of Nitrogenated Organobases: The Roles of Hydrogen Bonding and Proton Transfer

et al. 2021

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Alkylammonium cation affinities of 64 nitrogen‐containing organobases, as well as the respective proton transfer processes from the alkylammonium cations to the base, have been computed in the gas phase by using DFT methods. The guanidine bases show the highest proton transfer values (191.9–233 kJ mol−1) whereas the cis‐2,2’‐biimidazole presents the largest affinity towards the alkylammonium cations (>200 kJ mol−1) values. The resulting data have been compared with the experimentally reported proton affinities of the studied nitrogen‐containing organobases revealing that the propensity of an organobase for the proton transfer process increases linearly with its proton affinity. This work can provide a tool for designing senors for bioactive compounds containing amino groups that are protonated at physiological pH.

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Why ammonium detection is particularly challenging but insightful with ionophore-based potentiometric sensors – an overview of the progress in the last 20 years

Abstract: An overview of ionophore-based electrodes for ammonium sensing critically analyzing contributions in the last 20 years and with focus in analytical applications.

Cited by 51 publications

References 100 publications

Towards Clean and Safe Water: A Review on the Emerging Role of Imprinted Polymer-Based Electrochemical Sensors

Towards Clean and Safe Water: A Review on the Emerging Role of Imprinted Polymer-Based Electrochemical Sensors

Fabrication of an All-Solid-State Ammonium Paper Electrode Using a Graphite-Polyvinyl Butyral Transducer Layer

Alkylammonium Cation Affinities of Nitrogenated Organobases: The Roles of Hydrogen Bonding and Proton Transfer

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