In view of the problems existing in the artistic creation of modern art painting, such as poor composition, limited tools and materials, and improper color matching, this article proposed to apply computer vision technology to the art of art painting. Computer vision technology can simulate the visual process of living things, by sensing the environment, and using the relevant technologies contained therein to create two-dimensional (2D) images into three-dimensional (3D) information. Therefore, a comparative experiment was set up. The experimental results showed that when the sample images processed by computer vision technology were presented to the creator for viewing, the time taken by creator A and creator B to complete the artistic composition was 3.54 minutes and 3.66 minutes, respectively. When presenting the original unprocessed sample image to Creator C and Creator D for viewing, the time it took them to complete the artistic composition was 7.31 minutes and 8.63 minutes, respectively. It can be seen that the two creators of the former spend less time than the two creators of the latter, confirming that combining computer vision technology with artistic creation of art painting can not only expand the path of art painting materials, but also expand the thinking space of creators and improve creative efficiency. This article hoped that the application of computer vision technology in the creation of art painting can effectively promote the creative inspiration of creators, and explore new ideas for the art of art painting. This article provided a reference for the future development of art painting and artistic creation.