Whole‐tumor MRI histogram analyses of hepatocellular carcinoma: Correlations with Ki‐67 labeling index

Abstract

3 Technical Efficacy: Stage 3 J. MAGN. RESON. IMAGING 2017;46:383-392.

Value of MRI morphologic features with pT1‐2 rectal cancer in determining lymph node metastasis

“…Another study showed that DCE‐MRI had different patterns of early AP enhancement in benign and malignant LNs . It was also reported that tumor percent enhancement was helpful in assessing prognosis in hepatocellular carcinoma . Those studies revealed the role of gadolinium‐enhanced MRI on tumor prognosis.…”

“…19 It was also reported that tumor percent enhancement was helpful in assessing prognosis in hepatocellular carcinoma. 20 Those studies revealed the role of gadolinium-enhanced MRI on tumor prognosis. Our research demonstrated that tumors with a higher percent enhancement of AP were more likely to form new vessels from pre-existing ones, and thus were inclined to metastasize to LNs.…”

Histogram Analysis of Diffusion Kurtosis Magnetic Resonance Imaging for Diagnosis of Hepatic Fibrosis

“…However, routine MR signal measurements only provide mean values, which do not account for the underlying spatial distribution. MR histogram analysis is a new approach for quantification of the distribution of signal intensity of voxels using routinely acquired MR data, and refers to a mathematical approach to evaluate variations in gray-level intensity within a region of interest (ROI), which reflects histological heterogeneity ( 11 12 ). MR histogram analysis facilitated the detection and staging of liver fibrosis, confined to the application of gadoxetic acid-enhanced MRI and conventional DWI ( 13 14 15 ).…”

Histogram analyses of diffusion kurtosis indices and apparent diffusion coefficient in assessing liver regeneration after ALPPS and a comparative study with portal vein ligation

“…However, routine MR signal measurements only provide information for mean values. MR histogram analysis is an approach for quantifying the distribution of signal intensity of voxels, accounting for the underlying spatial distribution and intensity variations, which reflects the microstructural heterogeneity …”

“…MR histogram analysis is an approach for quantifying the distribution of signal intensity of voxels, accounting for the underlying spatial distribution and intensity variations, which reflects the microstructural heterogeneity. 16,17 The applications of DKI in liver are scarce and have kept some limited to in vitro studies. 14,18,19 Therefore, the purpose of this study was to investigate the value of DKI histogram analysis in assessing liver regeneration and functional compensation after ALPPS in comparison with PVL, as well as the potential intrinsic microstructure basis.…”