Whole transcriptome sequencing reveals the activity of the PLA2 family members in Androctonus crassicauda (Scorpionida: Buthidae) venom gland
Fatemeh Salabi,
Hedieh Jafari
Abstract:Phospholipase A2 is the most abundant venom gland enzyme, whose activity leads to the activation of the inflammatory response by accumulating lipid mediators. This study aimed to identify, classify, and investigate the properties of venom PLA2 isoforms. Then, the present findings were confirmed by chemically measuring the activity of PLA2. The sequences representing PLA2 annotation were extracted from the Androctonus crassicauda transcriptome dataset using BLAS searches against the local PLA2 database. We foun… Show more
“… Here, we compared the length of the discovered sequences from the venom of A. crassicauda . The PLA2 enzymatic activity in the venom of A. crassicauda was assessed in our last contribution [ 1 ]. …”
“… Here, we compared the length of the discovered sequences from the venom of A. crassicauda . The PLA2 enzymatic activity in the venom of A. crassicauda was assessed in our last contribution [ 1 ]. …”
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