Whole slide images for primary diagnostics in dermatopathology: a feasibility study

Abstract

Primary histopathological diagnosis of skin biopsies and resections can be done digitally using WSI.

Concordance between digital pathology and light microscopy in general surgical pathology: a pilot study of 100 cases

“…We have shown an acceptable concordance rate of 95% between conventional light microscopic assessment and digital pathology assessment. This rate of concordance is in line with other pilot studies of similar design, which have shown concordance rates ranging from 90% to 95% 4 7 20–24…”

Validation of whole slide imaging in the primary diagnosis of gynaecological pathology in a University Hospital

“…The results of our study are comparable with other validation studies conducted on skin,5 19 breast,14 26 prostate,17 27 urinary bladder,18 gastrointestinal8 20 and paediatric pathology,28 which show a high rate of concordance between WSI and CLM-based diagnoses. However, no previous studies have evaluated the accuracy of WSI diagnosis in the routine practice of gynaecological pathology, and neither are there any data about intraobserver or interobserver agreement in the evaluation of routine gynaecological specimens using CLM.…”

Whole slide images as a platform for initial diagnostics in histopathology in a medium-sized routine laboratory

“…In this hospital, digitisation of the whole daily production of histopathological specimens was initiated around the same time as in AMCH and has resulted in a situation where 75% of the diagnostics are performed digitally in addition to teleconsultations for frozen sections from other hospitals without local pathologists. Assessing the feasibility of primary WSI based diagnostics is ongoing currently in the University of Pittsburgh Medical Center, USA,5 University Medical Center Utrecht, The Netherlands16 17 19 and University Medical Center Nijmegen in collaboration with AMCH (manuscript in preparation). In addition, the Digital Pathology Association has presented two papers at the Pathology Vision conference 2011 discussing the high level validation approach of WSI for primary diagnostics.…”