Whole-Genome Sequencing and Mutation Analysis of Two Extensively Drug-Resistant Sputum Isolates of Mycobacterium tuberculosis (VRFCWCF XDRTB 232 and VRFCWCF XDRTB 1028) from Chennai, India

Abstract

We announce the draft genome sequence of two extensively drug-resistant Mycobacterium tuberculosis strains, VRFCWCF XDRTB 232 and VRFCWCF XDRTB 1028, isolated from the sputum samples of a patient clinically suspected to have tuberculosis, and we also report novel mutations that confer drug resistance.

Whole-Genome Sequence of a Beijing Extensively Drug-Resistant Mycobacterium tuberculosis Clinical Isolate from Buenaventura, Colombia

“…This is the second whole-genome sequencing report of a Beijing XDR-TB isolate circulating in Colombia ( 8 ). This will provide a foundation for comparative genomic analysis with XDR-TB genomes circulating in the Americas, as well as in other regions of the world ( 9 – 13 ).…”

Whole-Genome Sequencing of Two Latin American–Mediterranean Extensively Drug-Resistant Mycobacterium tuberculosis Clinical Isolates from Medellín, Colombia

“…This report on LAM sublineage XDR-TB Colombian isolates will provide material for comparative genomic analysis with other XDR-TB genomes circulating in Latin America and in other regions of the world ( 10 – 14 ).…”