Whole genome characterization of autochthonous Bos taurus brachyceros and introduced Bos indicus indicus cattle breeds in Cameroon regarding their adaptive phenotypic traits and pathogen resistance

Paguem, Archile; Abanda, Babette; Achukwi, Mbunkah Daniel; Baskaran, Praveen; Czemmel, Stefan; Renz, Alfons; Eisenbarth, Albert

doi:10.1186/s12863-020-00869-9

Cited by 8 publications

(3 citation statements)

References 48 publications

(89 reference statements)

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“…These regulatory proteins hold the reins in orchestrating cellular responses to a spectrum of stressors, with a primary focus on heat-induced stress [32]. The dynamic involvement of these transcription factors in modulating heat shock proteins during episodes of thermal stress has been documented across various African cattle populations [6,53,54]. Aside from the genes mentioned above, the DNAJC18 gene encodes for heat shock proteins that play vital roles in facilitating protein folding, directing misfolded proteins towards degradation pathways, and upholding protein equilibrium within the cellular environment.…”

Section: Discussionmentioning

confidence: 99%

Whole-Genome Resequencing Reveals Selection Signatures of Abigar Cattle for Local Adaptation

Ayalew,

Wu,

Tarekegn

et al. 2023

Animals

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Over time, indigenous cattle breeds have developed disease resistance, heat tolerance, and adaptability to harsh environments. Deciphering the genetic mechanisms underlying adaptive traits is crucial for their improvement and sustainable utilization. For the first time, we performed whole-genome sequencing to unveil the genomic diversity, population structure, and selection signatures of Abigar cattle living in a tropical environment. The population structure analysis revealed that Abigar cattle exhibit high nucleotide diversity and heterozygosity, with low runs of homozygosity and linkage disequilibrium, suggesting a genetic landscape less constrained by inbreeding and enriched by diversity. Using nucleotide diversity (Pi) and population differentiation (FST) selection scan methods, we identified 83 shared genes that are likely associated with tropical adaption. The functional annotation analysis revealed that some of these genes are potentially linked to heat tolerance (HOXC13, DNAJC18, and RXFP2), immune response (IRAK3, MZB1, and STING1), and oxidative stress response (SLC23A1). Given the wider spreading impacts of climate change on cattle production, understanding the genetic mechanisms of adaptation of local breeds becomes crucial to better respond to climate and environmental changes. In this context, our finding establishes a foundation for further research into the mechanisms underpinning cattle adaptation to tropical environments.

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Section: Discussionmentioning

confidence: 99%

Whole-Genome Resequencing Reveals Selection Signatures of Abigar Cattle for Local Adaptation

Ayalew,

Wu,

Tarekegn

et al. 2023

Animals

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“…The study was carried out on a total of 144 Bos indicus cows of 3 breed types (Goudali, Red and White Fulani). This is mainly because these breeds are the most common in Cameroon (Paguem et al, 2020). Amongst these were 50 pregnant cows and 94 non-pregnant cows all hailing from different places but mostly from the Adamawa region of Cameroon.…”

Section: Animal Materialsmentioning

confidence: 99%

Ovarian potential of Cameroonian Zebu cattle (Bos indicus) slaughtered in Etoudi – Yaoundé

Katte,

Herve,

Dorice

et al. 2023

J Anim Reprod Biotechnol

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Background: This study helps to evaluate the Ovarian potential of Cameroonian Zebu cattle (Bos indicus) slaughtered in Etoudi -Yaoundé for implementing Assisted Reproductive Techniques (ARTs). The aim was to enhance the productivity of the cattle sub-sector in Cameroon while conserving local genetic resources. Methods: A total of 144 cows, including 94 cycled cows and 50 pregnant cows, were included in the study. Live weights were determined by measuring the thoracic perimeter of each cow using a Rondo measuring tape. Age was determined postmortem through examination of dentition and horns, while the uterus and ovaries were removed, weighed, and classified based on physiological status (pregnant or nonpregnant). Follicles were counted, and their diameters were measured and categorized into small (Ø < 3 mm), medium (Ø 3-8 mm), and large (Ø > 8 mm). Results: The results revealed an average follicular population of 32.02 ± 9.31 per cow, with 22.43 ± 8.45 small follicles, 8.42 ± 3.87 medium follicles, and 0.76 ± 0.34 large follicles. The weight of the right ovary was significantly higher than that of the left ovary (p < 0.05), and cows aged 6 to 9 years exhibited a higher number of follicles compared to other age groups. Cows with medium (BCS = 3) and large (BCS = 4-5) body reserves had the heaviest ovaries. Additionally, pregnant cows had heavier uteri compared to non-pregnant cows, and cows with a body condition score of 3 or higher had higher uterine weights than lean cows (BCS = 1-2). Conclusions: This study demonstrates that age, body condition score, and pregnancy status influence ovarian weight. Body Condition Score serves as a reliable indicator of cow nutritional status, and cows with BCS of 3-5 are excellent candidates for in vitro production of embryos.

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“…Genetic diversity, introgression, and relationships with Bos taurus were studied using genotype information on 28 markers (16 microsatellite, 7 milk protein, and 5 blood protein markers) by Ibeagha-Awemu et al [ 11 ]. Paguem et al characterized the whole genome of Bos indicus indicus breed of Cameroon focusing on their adaptive phenotypic traits and pathogen resistance [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

Using Bioelements Isotope Ratios and Fatty Acid Composition to Deduce Beef Origin and Zebu Feeding Regime in Cameroon

et al. 2021

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The purpose of this study was to address the lack of knowledge regarding the stable isotopic composition of beef from zebu cattle reared in tropical Africa. Sixty beef carcasses belonging to the most common zebu breeds (Goudali, white Fulani, and red Mbororo) were selected and classified according to their subcutaneous fat color (white, cream or yellow). The stable isotope ratios of five bioelements—H, O, C, N, and S—in muscle fractions and the fatty acids composition were analyzed. Zebu meat from Cameroon shows peculiar δ13C values, related to the almost exclusive intake of grazed tropical grasses with photosynthetic cycle C4. It also shows δ2H and δ18O values higher than those reported in other areas of the world and correlated with the isotopic composition of animal drinking water. The white subcutaneous fat (“white type”) zebu showed higher δ2H and lower δ13C than the “yellow type”, that is correlated with a higher content of polyunsaturated fatty acid (PUFA) and a lower amount of saturated fatty acid (SFA) and monounsaturated fatty acid (MUFA). Multielement analysis seems to provide promising results for tracing the regional origin of Cameroon beef and some aspects of the livestock system, such as the nutritional status of the animals.

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Whole genome characterization of autochthonous Bos taurus brachyceros and introduced Bos indicus indicus cattle breeds in Cameroon regarding their adaptive phenotypic traits and pathogen resistance

Cited by 8 publications

References 48 publications

Whole-Genome Resequencing Reveals Selection Signatures of Abigar Cattle for Local Adaptation

Whole-Genome Resequencing Reveals Selection Signatures of Abigar Cattle for Local Adaptation

Ovarian potential of Cameroonian Zebu cattle (Bos indicus) slaughtered in Etoudi – Yaoundé

Using Bioelements Isotope Ratios and Fatty Acid Composition to Deduce Beef Origin and Zebu Feeding Regime in Cameroon

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