Whole-brain structure–function coupling abnormalities in mild cognitive impairment: a study combining amplitude of low-frequency fluctuations and voxel-based morphometry
Rong Zhao,
Pan Wang,
Lin Liu
et al.
Abstract:Alzheimer’s disease (AD), one of the leading diseases of the nervous system, is accompanied by symptoms such as loss of memory, thinking and language skills. Both mild cognitive impairment (MCI) and very mild cognitive impairment (VMCI) are the transitional pathological stages between normal aging and AD. While the changes in whole-brain structural and functional information have been extensively investigated in AD, The impaired structure–function coupling remains unknown. The current study employed the OASIS-… Show more
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