Whole-body Vibration Training as a Supportive Therapy During Allogeneic Haematopoietic Stem Cell Transplantation – A Randomised Controlled Trial

Kaeding, Tobias S.; Frimmel, Marcel; Treondlin, Florian; Jung, Klaus; Jung, Wolfram; Wulf, Gerald; Trümper, Lorenz; Hasenkamp, Justin

doi:10.17925/eoh.2018.14.1.33

Cited by 4 publications

(7 citation statements)

References 43 publications

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“…Of these, we assessed n = 195 for eligibility based on the full text. A total of n = 39 studies of the following types met the inclusion criteria [ 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 ]: n = 24 randomized clinical trials, n = 9 pilot studies, and n = 6 feasibility studies ( Table 1 ). In these 39 studies, n = 84 different outcomes were used 227 times and were measured using n = 125 different instruments ( Table 2 ).…”

Section: Resultsmentioning

confidence: 99%

“…EORTC QLQ-C30 [16,31,36,37] Feasibility [16] RCT [31,36,37] Hospital [16,31,36] Throughout [37] Exercise [16] Multimodal Intervention [31] Whole Body Vibration Training [36] Self-administered exercise [37] Santa mina et al, Kaeding et al, 2018Wiskemann et al, 2011 Anxiety [16,33,38]…”

Section: Resultsmentioning

confidence: 99%

“…Spirometry [32,51] RCT [32,51] Hospital [51] Inpatient post [32] Exercise Training [51] Inspiratory muscle training [32] Baumann et al, 2011 Bargi et al, 2015 Aerobic endurance performance capacity [36] The 6-Minute Walk Test [36] RCT [36] Hospital [36] Whole Body Vibration Training [36] Kaeding et al, 2018…”

Section: Pulmonarymentioning

confidence: 99%

“…Performance [36] Biodex System [36] RCT [36] Hospital [36] Whole Body Vibration Training [36] Kaeding et al, 2018…”

Section: Isokinetic Legmentioning

confidence: 99%

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A Scoping Review on Outcomes and Outcome Measurement Instruments in Rehabilitative Interventions for Patients with Haematological Malignancies Treated with Allogeneic Stem Cell Transplantation

et al. 2022

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Rationale: Allogeneic hematopoietic stem cell transplantation (HSCT) is associated with increased treatment-related mortality, loss of physical vitality, and impaired quality of life. Future research will investigate the effects of multidisciplinary rehabilitative interventions in alleviating these problems. Nevertheless, published studies in this field show considerable heterogeneity in selected outcomes and the outcome measurement instruments used. The purpose of this scoping review is to provide an overview of the outcomes and outcome measurement instruments used in studies examining the effects of rehabilitative interventions for patients treated with allogeneic HSCT. Methods: We conducted a scoping review that included randomized controlled trials, pilot studies, and feasibility studies published up to 28 February 2022. Results: We included n= 39 studies, in which n = 84 different outcomes were used 227 times and n = 125 different instruments were used for the measurements. Conclusions: Research in the field of rehabilitation for patients with haematological malignancies treated with allogeneic HSCT is hampered by the excess outcomes used, the inconsistent outcome terminology, and the inconsistent use of measurement instruments in terms of setting and timing. Researchers in this field should reach a consensus with regard to the use of a common terminology for the outcomes of interest and a homogeneity when selecting measurement instruments and measurement timing methods.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Pulmonarymentioning

confidence: 99%

“…Performance [36] Biodex System [36] RCT [36] Hospital [36] Whole Body Vibration Training [36] Kaeding et al, 2018…”

Section: Isokinetic Legmentioning

confidence: 99%

See 2 more Smart Citations

A Scoping Review on Outcomes and Outcome Measurement Instruments in Rehabilitative Interventions for Patients with Haematological Malignancies Treated with Allogeneic Stem Cell Transplantation

et al. 2022

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“…These results may indicate that the functional benefits from standard exercise interventions are more evident when used early in the patients' trajectory. 12 Kaeding et al 13 (University of Oldenburg, Oldenburg, Germany) presented data from whole body vibration training for the prevention of cancer cachexia during allogeneic hematopoietic stem cell transplantation. The aim of this study was to examine whether performing whole body vibration training on every second day of hospitalization in combination with classic general physiotherapy assists in stabilizing the physical capacity of patients undergoing haematopoietic stem cell transplantation.…”

Section: Body Compositionmentioning

confidence: 99%

Unlocking the wasting enigma: Highlights from the 8th Cachexia Conference

Ebner¹,

Haehling²

2016

Journal of Cachexia, Sarcopenia and Muscle

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This article highlights pre‐clinical and clinical studies into the field of wasting disorders that were presented at the 8th Cachexia Conference held in Paris, France December 2015. This year some interesting results of clinical trials and different new therapeutic targets were shown. This article presents the biological and clinical significance of different markers and new drugs for the treatment of skeletal muscle wasting. Effective treatments of cachexia and wasting disorders are urgently needed in order to improve the patients' quality of life and their survival.

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People With Hematological Malignancies Treated With Bone Marrow Transplantation Have Improved Function, Quality of Life, and Fatigue Following Exercise Intervention: A Systematic Review and Meta-Analysis

et al. 2021

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Objective For people with hematological malignancies treated with bone marrow transplantation (BMT), this systematic review aimed to identify, evaluate, and synthesize the evidence examining the effect of exercise training on the outcomes of exercise capacity, health-related quality of life (HRQoL), and hospital length of stay and to identify any difference in the effect on people treated with allogeneic versus autologous transplantation. Methods Five electronic databases were systematically searched from inception to December 5, 2020. Prospective studies with a comparator group, with or without randomization, were included if they investigated the effects of an exercise intervention compared with usual care or another intervention in adults who had a hematological malignancy and were undergoing BMT. Primary outcomes of interest were functional exercise capacity and HRQoL; secondary outcomes included strength, fatigue, hospital length of stay, and feasibility. Only randomized controlled trials were included in the meta-analyses. Risk of bias was evaluated using the Physiotherapy Evidence Database or Newcastle-Ottawa Scale; quality of evidence for meta-analyses was assessed using the Grading of Recommendations Assessment, Development and Evaluation approach. Results Twenty-four randomized controlled trials and 3 prospective nonrandomized experimental trials were included (n = 2432). There was moderate-quality evidence that exercise improves functional exercise capacity (mean difference [MD] = 29 m; 95% CI = 12.59 to 45.4), global HRQoL (MD = 3.38 points; 95% CI = 0.37 to 6.39), and fatigue (MD = 2.52 points; 95% CI = 0.42 to 4.63) and low-quality evidence for reduced hospital length of stay (MD = 2.07 days; 95% CI = 0.43 to 3.72). These effects were more pronounced in recipients of allogeneic transplantation. No serious adverse events were associated directly with exercise in the included studies. Conclusions Exercise is safe and improves outcomes, including functional exercise capacity, HRQoL, and hospital length of stay, in adults undergoing BMT. Impact The results of this systematic review support the implementation of exercise programs in adults undergoing BMT, particularly recipients of allogeneic transplantation.

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Whole-body Vibration Training as a Supportive Therapy During Allogeneic Haematopoietic Stem Cell Transplantation – A Randomised Controlled Trial

Cited by 4 publications

References 43 publications

A Scoping Review on Outcomes and Outcome Measurement Instruments in Rehabilitative Interventions for Patients with Haematological Malignancies Treated with Allogeneic Stem Cell Transplantation

A Scoping Review on Outcomes and Outcome Measurement Instruments in Rehabilitative Interventions for Patients with Haematological Malignancies Treated with Allogeneic Stem Cell Transplantation

Unlocking the wasting enigma: Highlights from the 8th Cachexia Conference

People With Hematological Malignancies Treated With Bone Marrow Transplantation Have Improved Function, Quality of Life, and Fatigue Following Exercise Intervention: A Systematic Review and Meta-Analysis

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