Whole-Body Vibration Therapy for Osteoporosis: State of the Science

Wysocki, Andrea; Butler, Mary; Shamliyan, Tatyana; Kane, Robert L

doi:10.7326/0003-4819-155-10-201111150-00006

Cited by 73 publications

(78 citation statements)

References 59 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It has been welldocumented that adolescents with DS have lower levels of muscle strength and poor bonehealth, and so early interventions to stimulate muscle strength and bone accrual are of clinical importance in preventing osteoporosis [14]. Wysocki et al [13] stated that the optimal target population for the WBV training has not been defined, while Slatkosvka et al…”

Section: Discussionmentioning

confidence: 99%

“…Methods 26 adolescents (13 DS;(12)(13)(14)(15)(16)(17)(18) were measured with dual-energy x-ray absorptiometry before and after the intervention (3/week, 10 repetitions (30-60 seconds) and 1-min rest, frequency 25-30 Hz, and peak-to-peak displacement of 2 mm (peak acceleration 2.5-3.6 g)). Both, an intention-to-treat (ITT) analysis designed to assess the effects on bone mass, and a per-protocol analysis, designed to compare poor-and high-compliers, were performed.…”

Section: Introductionmentioning

confidence: 99%

“…Low-amplitude highfrequency whole body vibration (WBV) training is recently receiving much attention for treating low levels of bone mass [13]. Nowadays, WBV has been applied mainly as a therapy method in children and adolescents with disabling conditions [14] and also in seniors [15,16].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Effect of whole-body vibration training on bone mass in adolescents with and without Down syndrome: a randomized controlled trial

et al. 2015

View full text Add to dashboard Cite

Abstract:Introduction This study aims to observe the differences between adolescents with and without Down syndrome (DS) in the effects of 20 weeks of whole-body vibration (WBV) training, on bone mineal content (BMC), and density (BMD). Methods 26 adolescents (13 DS;(12)(13)(14)(15)(16)(17)(18) were measured with dual-energy x-ray absorptiometry before and after the intervention (3/week, 10 repetitions (30-60 seconds) and 1-min rest, frequency 25-30 Hz, and peak-to-peak displacement of 2 mm (peak acceleration 2.5-3.6 g)). Both, an intention-to-treat (ITT) analysis designed to assess the effects on bone mass, and a per-protocol analysis, designed to compare poor-and high-compliers, were performed. Results The ITT analysis revealed significant increases in all BMC and BMD parameters (dz = 0.66 to 1.64; all p<0.05) in the non-DS group, whilst DS group improved whole-body, subtotal (whole-body less head), upper limbs (ULIMBS), pelvis, lower limbs (LLIMBS) and spine BMC (dz = 0.75 to 1.76; all p<0.05) and subtotal, pelvis, LLIMBS, and spine BMD (dz = 0.73 to 1.28; all p<0.05). Significantly greater increases were evident in the absolute and percent changes of the non-DS group over DS group (d = 0.88 to 3.85; all p<0.05). ULIMBS BMD showed a tendency towards an interaction (f = 0.41 and p = 0.086) with higher increase for non-DS group. When a per-protocol analysis was considered, high-complier adolescents had 8.1 versus 5. Dear Editor, Please, find attached a revised version of our manuscript entitled "Effect of whole-body vibration training on bone mass in adolescents with and without Down syndrome: a randomized controlled trial" to be reconsidered for publication in your prestigious journal.We have taken into account all the comments made from the reviewer and a point-bypoint response has been attached to our submission. In addition, we have highlighted in yellow the pertinent changes in the main manuscript for an easier revision. This manuscript represents original unpublished material; is not under consideration for publication elsewhere, and further, it will not be submitted for publication elsewhere until a decision is made regarding its acceptability for publication in your Journal. The manuscript presented by Matute-Llorente and colleagues is clearly of interest to people working in all health related disciplines. The manuscript provides an interesting argument in the understanding of the relationship between Down syndrome changes in bone mass after vibration training. The structure of the document is well written and follows an appropriate structure that makes for an easy, detailed and informative read. Response: Thank you very much for your revision of our manuscript. All your comments have been addressed and explained below. Also, the changes have been highlighted in yellow in the manuscript in order to make easier the revision process. MINOR CONCERNS:P4L49 how will gender impact the changes in BMD between these two groups? R: Thanks for your comment, we have realised the excessive length and lack of clarit...

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effect of whole-body vibration training on bone mass in adolescents with and without Down syndrome: a randomized controlled trial

et al. 2015

View full text Add to dashboard Cite

show abstract

“…Hz (0.3 g) similar to those used in clinical studies [9,30,31]. The duration and frequency of sessions was selected based on our recent publication [18], where we demonstrated an ability of WBV to improve selected biomarkers of bone turnover and gene expression and to reduce osteoclastogenesis after spinal cord injury.…”

Section: Methodsmentioning

confidence: 99%

Whole Body Vibration Therapy after Ischemia Reduces Brain Damage in Reproductively Senescent Female Rats

Raval¹,

Schatz²,

Bhattacharya³

et al. 2018

Preprint

View full text Add to dashboard Cite

A risk of ischemic stroke increases exponentially after menopause. Even a mild-ischemic stroke can result in increased frailty. Frailty is a state of increased vulnerability to adverse outcomes, which subsequently increases risk of cerebrovascular events and severe cognitive decline, particularly after menopause.Several interventions to reduce frailty and subsequent risk of stroke and cognitive decline have been proposed in laboratory animals and patients. One of them is whole body vibration (WBV). WBV improves brain hemodynamics and lessens frailty-related functional and cognitive deterioration. The goal of current study is to test the efficacy of WBV in reducing post-ischemic stroke frailty and brain damage in reproductively senescent female rats. Reproductively senescent Sprague-Dawley female rats were exposed to transient middle cerebral artery occlusion (tMCAO) and randomly assigned to either WBV or control groups. Animals placed in the WBV group underwent 30 days of WBV (40 Hz) treatment performed twice daily for 15 min each session for 5 days each week. The motor functions of animals belonging to both groups were tested intermittently and at the end of treatment period. Brains were then harvested for inflammatory markers and histopathological analysis. The results demonstrate a significant reduction in inflammatory markers, infarct volume, and significant increases in brain-derived neurotrophic factor and improvement in functional activity after tMCAO in middle-aged female rats that were treated with WBV as compared to the control group. Our results may help faster translation of the WBV intervention for improved outcome after stroke, particularly among frail women.

show abstract

“…WBV is assumed to improve, among other things, muscle strength, bone density, blood flow and mobility [1][2][3][4]. The focuses during therapy are on preventing or reducing osteoporosis [5,6], on muscle training [7] to prevent falls and the resulting bone fractures [8], and on the prevention of back pain [9]. WBV activates muscles and may lead to rapid accelerations of body segments [6,10].…”

Section: Introductionmentioning

confidence: 99%

In vivo measurements of the effect of whole body vibration on spinal loads

et al. 2013

View full text Add to dashboard Cite

Purpose It is assumed that whole body vibration (WBV) improves muscle strength, bone density, blood flow and mobility and is therefore used in wide ranges such as to improve fitness and prevent osteoporosis and back pain. It is expected that WBV produces large forces on the spine, which poses a potential risk factor for the health of the spine. Therefore, the aim of the study was to measure the effect of various vibration frequencies, amplitudes, device types and body positions on the loads acting on a lumbar vertebral body replacement (VBR). Methods Three patients suffering from a fractured lumbar vertebral body were treated using a telemeterized VBR. The implant loads were measured during WBV while the patients stood on devices with vertically and seesawinduced vibration. Frequencies between 5 and 50 Hz and amplitudes of 1, 2 and 4 mm were tested. The patients stood with their knees straight, slightly bent, or bent at 60°. In addition, they stood on their forefeet. Results The peak resultant forces on the implant increased due to vibration by an average of 24 % relative to the forces induced without vibration. The average increase of the peak implant force was 27 % for vertically induced vibration and 15 % for seesaw vibration. The forces were higher when the legs were straight than when the knees were bent. Both the vibration frequency and the amplitude had only a minor effect on the measured forces. Conclusions The force increase due to WBV is caused by an activation of the trunk muscles and by the acceleration forces. The forces produced during WBV are usually lower than those produced during walking. Therefore, the absolute magnitude of the forces produced during WBV should not be harmful, even for people with osteoporosis.

show abstract

Whole-Body Vibration Therapy for Osteoporosis: State of the Science

Cited by 73 publications

References 59 publications

Effect of whole-body vibration training on bone mass in adolescents with and without Down syndrome: a randomized controlled trial

Effect of whole-body vibration training on bone mass in adolescents with and without Down syndrome: a randomized controlled trial

Whole Body Vibration Therapy after Ischemia Reduces Brain Damage in Reproductively Senescent Female Rats

In vivo measurements of the effect of whole body vibration on spinal loads

Contact Info

Product

Resources

About