Whole-body MRI in Pediatric Patients with Chronic Recurrent Multifocal Osteomyelitis

Whole-Body MRI at Initial Presentation of Chronic Recurrent Multifocal Osteomyelitis, Juvenile Idiopathic Arthritis, Their Overlapping Syndrome, and Non-Specific Arthropathy

“…CRMO is the entity to which relatively most publications on the use of WB-MRI have been devoted. The disease is generally more common in boys; in our study, CRMO was slightly more frequently diagnosed in boys (58% vs. 42%), similarly to the results of Tasar et al [41] (65%).…”

“…Spondylitis was the only lesion seen in our series. In our initial WB-MRI, we did not find spondylodiscitis, sclerotic/nonactive lesions, paravertebral ossifications, or osteolytic lesions with variable degrees of vertebral body collapse, commonly seen in the thoracic spine by other groups [10,41]. Such changes generally arise in up to 40% of patients with the disease duration, including structural vertebral body deformities extending from wedging to crush fractures [8].…”

“…Enthesitis was found in only 1 of 26 patients (3.8%). No patients had any clinical or radiological evidence of enthesitis in the study by Tasar et al [41].…”

“…Mild joint effusion was seen in only five patients (25%) by Papakonstantinou et al [44], with nearby bones being affected (three ankles, one hip, and one knee joint). In the Tasar et al study [41], joint involvement was present in 20 patients (14%), The sacroiliac joint was the most commonly involved, followed by the knee, the sternoclavicular joint, and the ankle.…”

“…The pelvis was one of the commonest sites of involvement in several studies, ranging from 15% to 40% [10,13,41,43,44]. Typical sites of CRMO involvement include metaphyseal equivalents, pelvic synchondroses, and the sacroiliac joints, of which the latter resembles inflammatory sacroiliitis [8].…”