Whole‐body MRI for staging Hodgkin lymphoma in a pregnant patient

Vermoolen, Malou A.; Kwee, Thomas C.; Nievelstein, Rutger A.J.

doi:10.1002/ajh.21677

Cited by 5 publications

(2 citation statements)

References 3 publications

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“…HL is more common than non-HL and has an estimated prevalence of 1 per 6000 pregnancies. 2 However, there are few published reports 3 – 9 regarding lymphoma-specific data during pregnancy, concerning diagnosis, management, optimal timing of therapy, complications and outcomes when chemotherapy is started during gestation.…”

Section: Discussionmentioning

confidence: 99%

Whole-body magnetic resonance for staging and response assessment of lymphoma in a pregnant woman treated with antenatal chemotherapy

et al. 2017

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A 32-year-old pregnant female presented with bilateral supraclavicular swelling, diffuse itching and right shoulder pain. After lymph nodal biopsy, a diagnosis of nodular sclerosis Hodgkin’s lymphoma was obtained. A multidisciplinary team decided to start chemotherapy before the delivery, and whole-body MRI was used to stage the disease and evaluate the response after antenatal chemotherapy. This case shows that whole-body MRI is an attractive procedure that avoids radiation exposure and contrast administration, and enables staging and follow-up of a pregnant patient without risk to the fetus.

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Section: Discussionmentioning

confidence: 99%

Whole-body magnetic resonance for staging and response assessment of lymphoma in a pregnant woman treated with antenatal chemotherapy

et al. 2017

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“…Abdominal ultrasonography can identify the extent and size of retroperitoneal nodal disease with sufficient detail for proper management [24]. Magnetic resonance imaging (MRI) without use of gadolinium can also be used if further detailed imaging is required [25]. …”

Section: Treatment Of Hodgkin Lymphoma Patients With Coincident Prmentioning

confidence: 99%

Hodgkin lymphoma in the elderly, pregnant, and HIV-infected

Bachanová

Connors

2016

Seminars in Hematology

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Hodgkin lymphoma (HL) presenting in patients with co-incidental advanced age, pregnancy, or human immunodeficiency virus (HIV) infection is uniquely challenging to manage. In this article we integrate recent evidence and clinical expertise to present recommendations for diagnosis and therapeutic management. Older patients with HL need to be carefully evaluated for comorbidies after which judicious choice of chemotherapy should minimize functional compromise. A pregnant patient with concurrent HL should be staged with minimal use of imaging requiring ionizing radiation and treated in an individualized manner optimally combining the strategies of treatment deferral when appropriate, use of single-agent vinblastine for symptomatic disease and reservation of multi-agent chemotherapy for the small minority of patients with aggressive clinical presentation. Treatment of HL coincident with HIV infection requires a combination of highly active anti-retroviral agents (HAART), standard multi-agent chemotherapy with meticulous attention to drug–drug interactions, and vigorous supportive care to ensure the best chance of cure.

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