Whole-body MRI and pathological findings in adult patients with myopathies

Tomás, Xavier; Milisenda, José C.; García-Diez, Ana Isabel; Prieto-González, Sergio; Faruch, Marie; Pomés, Jaime; Grau-Junyent, Josep María

doi:10.1007/s00256-018-3107-1

Cited by 25 publications

(10 citation statements)

References 90 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The standard WB-MRI protocols for IM usually comprises coronal and axial FSE T1-weighted images and STIR sequences. 71,72 The use of a 3D STIR sequence is of crucial interest in patients with IM, to limit the number of acquisitions that are required. Quantitative MRI sequences evaluating the skeletal muscles are promising for patients with IM.…”

Section: Inflammatory Myopathiesmentioning

confidence: 99%

3D Whole-Body MRI of the Musculoskeletal System

Pasoglou

Nieuwenhove

Peeters

et al. 2021

Semin Musculoskelet Radiol

View full text Add to dashboard Cite

With its outstanding soft tissue contrast, spatial resolution, and multiplanar capacities, magnetic resonance imaging (MRI) has become a widely used technique. Whole-body MRI (WB-MRI) has been introduced among diagnostic methods for the staging and follow-up assessment in oncologic patients, and international guidelines recommend its use. In nononcologic applications, WB-MRI is as a promising imaging tool in inflammatory diseases, such as seronegative arthritis and inflammatory myopathies. Technological advances have facilitated the introduction of three-dimensional (3D) almost isotropic sequences in MRI examinations covering the whole body. The possibility to reformat 3D images in any plane with equal or almost equal resolution offers comprehensive understanding of the anatomy, easier disease detection and characterization, and finally contributes to correct treatment planning. This article illustrates the basic principles, advantages, and limitations of the 3D approach in WB-MRI examinations and provides a short review of the literature.

show abstract

Section: Inflammatory Myopathiesmentioning

confidence: 99%

3D Whole-Body MRI of the Musculoskeletal System

Pasoglou

Nieuwenhove

Peeters

et al. 2021

Semin Musculoskelet Radiol

View full text Add to dashboard Cite

show abstract

“…WB-MRI can effectively provide information that is enormously useful to clinical evaluation, detecting all areas of inflammatory involvement or fat replacement throughout the body, greatly helping in the diagnostic process (237). It consequently allows a better tailoring of eventual treatments, and, last but not least, a better monitoring of their efficacy, in a reasonably short time.…”

Section: Applications Of Advanced Quantitative Techniquesmentioning

confidence: 99%

Advances in Quantitative Imaging of Genetic and Acquired Myopathies: Clinical Applications and Perspectives

et al. 2019

View full text Add to dashboard Cite

In the last years, magnetic resonance imaging (MRI) has become fundamental for the diagnosis and monitoring of myopathies given its ability to show the severity and distribution of pathology, to identify specific patterns of damage distribution and to properly interpret a number of genetic variants. The advances in MR techniques and post-processing software solutions have greatly expanded the potential to assess pathological changes in muscle diseases, and more specifically of myopathies; a number of features can be studied and quantified, ranging from composition, architecture, mechanical properties, perfusion, and function, leading to what is known as quantitative MRI (qMRI). Such techniques can effectively provide a variety of information beyond what can be seen and assessed by conventional MR imaging; their development and application in clinical practice can play an important role in the diagnostic process and in assessing disease course and treatment response. In this review, we briefly discuss the current role of muscle MRI in diagnosing muscle diseases and describe in detail the potential and perspectives of the application of advanced qMRI techniques in this field.

show abstract

“…40 The technique provides an estimation of the total disease burden with a single study, seeking specific distribution patterns including clinically silent involvement of muscle areas. 41,42 Furthermore, during follow-up, WB-MRI can help select the target muscle area for biopsy and can detect related and nonrelated pathologic conditions such as tumors. STIR and DWI sequences are very sensitive in detecting active muscle inflammation, yielding clinical benefits in the study of myopathies.…”

Section: Inflammatory Skeletal Disordersmentioning

confidence: 99%

Update on Whole-body MRI in Musculoskeletal Applications

Vilanova

García‐Figueiras

Luna

et al. 2019

Semin Musculoskelet Radiol

View full text Add to dashboard Cite

Whole-body magnetic resonance imaging (WB-MRI) is a powerful tool increasingly used to assess oncologic and nononcologic diseases. WB-MRI provides information about diffuse multifocal pathologies with excellent anatomical definition through high soft tissue contrast and spatial resolution as well as valuable functional information from diffusion-weighted images. In addition to its roles in establishing the diagnosis and assessing the extent and severity of disease, WB-MRI is also useful for monitoring the response to treatment for malignant and benign systemic diseases affecting the musculoskeletal system. This article reviews and updates the applications of WB-MRI in current practice, discussing the role of this helpful tool in various conditions involving the musculoskeletal system including bone metastases, hematologic cancers, inflammatory processes, infections, and multisystemic-multifocal bone, nerve, vascular, and muscle/soft tissue disorders, as well as other idiopathic conditions.

show abstract

Whole-body MRI and pathological findings in adult patients with myopathies

Cited by 25 publications

References 90 publications

3D Whole-Body MRI of the Musculoskeletal System

3D Whole-Body MRI of the Musculoskeletal System

Advances in Quantitative Imaging of Genetic and Acquired Myopathies: Clinical Applications and Perspectives

Update on Whole-body MRI in Musculoskeletal Applications

Contact Info

Product

Resources

About