White matter hyperintensities modify relationships between corticospinal tract damage and motor outcomes after stroke
Jennifer K. Ferris,
Bethany P. Lo,
Giuseppe Barisano
et al.
Abstract:Motor outcomes after stroke relate to corticospinal tract (CST) damage. Concurrent damage from white matter hyperintensities (WMHs) might impact neurological capacity for recovery after CST injury. Here, we evaluated if WMHs modulate the relationship between CST damage and post-stroke motor impairment outcome.We included 223 individuals from the ENIGMA Stroke Recovery Working Group. CST damage was indexed with weighted CST lesion load (CST-LL). Mixed effects beta-regression models were fit to test the impact o… Show more
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