2012
DOI: 10.1038/npp.2012.241
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White Matter Abnormalities in Skin Picking Disorder: A Diffusion Tensor Imaging Study

Abstract: Skin picking disorder (SPD) is characterized by the repetitive and compulsive picking of skin, resulting in tissue damage. Neurocognitive findings in SPD implicate difficulty with response inhibition (suppression of pre-potent motor responses). This function is dependent on the integrity of the right frontal gyrus and the anterior cingulate cortices, and white-matter tracts connecting such neural nodes. It was hypothesized that SPD would be associated with reduced fractional anisotropy in regions implicated in… Show more

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Cited by 70 publications
(57 citation statements)
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“…18,26 One could argue that, in a classification system used globally in primary care contexts, skin picking and trichotillomania could be combined into a single pathological grooming disorder. Although there is evidence for a possible shared biology between skin-picking disorder and trichotillomania, 27 there are also important differences between these disorders, including different gender ratios, different ages of onset, cognitive differences, and possible unique genetic contributions. 28,29 DSM-5 included skin-picking disorder as a separate disorder because of evidence for its unique biology and clinical presentation.…”
Section: Skin-picking Disordermentioning
confidence: 99%
“…18,26 One could argue that, in a classification system used globally in primary care contexts, skin picking and trichotillomania could be combined into a single pathological grooming disorder. Although there is evidence for a possible shared biology between skin-picking disorder and trichotillomania, 27 there are also important differences between these disorders, including different gender ratios, different ages of onset, cognitive differences, and possible unique genetic contributions. 28,29 DSM-5 included skin-picking disorder as a separate disorder because of evidence for its unique biology and clinical presentation.…”
Section: Skin-picking Disordermentioning
confidence: 99%
“…Eksen 1 ek tanısını dışlayarak yapılan bir çalışmada psikopatolojinin özgül olmayan bir belirti olarak kavramsallaştırılmasının uygun olmayacağı sonucuna varılmıştır. [32,33] Arnold ve arkadaşlarının, [17], duygudurum bozukluğunun hastaların yarısından fazlasında, deri yolmanın ortaya çıkmasından yaklaşık bir yıl önce başla-dığına ilişkin bulguları bu konuda daha fazla çalışma yapılmasına gereksinim olduğunu düşündürmektedir.…”
Section: Ek Tanılarunclassified
“…Bu bulgular, deri yolma bozukluğunun patofizyolojisinde, motor yanıtı başlatma ve baskılama ile ilişkili beyaz madde alanlarında bir organizasyon bozukluğunun olduğunu desteklemektedir. [32] …”
Section: Etyolojiunclassified
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“…11.029 0166-4328/© 2014 Elsevier B.V. All rights reserved. has noted that the two disorders have similar clinical features [2][3][4].…”
Section: Introductionmentioning
confidence: 99%