White blood cell count to mean platelet volume ratio as a novel non-invasive marker predicting long-term outcomes in patients with non-ST elevation acute coronary syndrome

Abstract

(p < 0.001). In an adjusted cox regression model, the elevated WMR was independently predicted the incidence of MACE (hazard ratio 2.419, p < 0.001). Conclusions:The elevated baseline WMR independently predicted the MACE incidence in patients with NSTE-ACS during long-term follow-up. (Cardiol J 2015; 22, 4: 437-445) Key words: white blood cell to mean platelet volume ratio, non-ST elevation acute coronary syndrome, major adverse cardiovascular events

White blood cell count to mean platelet volume ratio: A novel and promising prognostic marker for ST-segment elevation myocardial infarction

“…Increased WBCs may appear as a significant factor showing impaired microvascular reperfusion. Recently, Dehghani et al [11] investigated a novel parameter called WMR as a marker predicting long-term outcomes in patients with NSTEMI. They suggested that WMR is a better predictor of worse outcomes in patients with NSTEMI than WBC and MPV [11].…”

“…Recently, Dehghani et al [11] investigated a novel parameter called WMR as a marker predicting long-term outcomes in patients with NSTEMI. They suggested that WMR is a better predictor of worse outcomes in patients with NSTEMI than WBC and MPV [11]. In light of these evidences, we decided to evaluate the prognostic value of WMR with a large number of patients with STEMI undergoing pPCI and demonstrated that WMR is a better indicator of predicting the poor outcomes in STEMI than MPV, RDW, PLR-NLR and WBC-MPV combinations.…”

“…Apart from WBC count, other blood count parameters such as neutrophil count, red blood cell distribution with (RDW), mean platelet volume (MPV), high neutrophil to lymphocyte ratio (NLR) and high platelet to lymphocyte ratio (PLR) also seem to have prognostic value in STEMI [6][7][8][9][10]. As a combination of both WBC and mean platelet volume, WBC count to mean platelet volume ratio (WMR) has been recently found as a novel non-invasive marker predicting long-term outcomes in patients with non-ST elevation myocardial infarction (NSTEMI) [11]. Until now, the use of this marker for cardiovascular (CV) prognosis has not been investigated in patients undergoing primary percutaneous coronary intervention (pPCI) for STEMI.…”

The prognostic value of white blood cell count-to-mean platelet volume ratio in patients with acute coronary syndrome

“…We have read the article entitled "White blood cell count to mean platelet volume ratio as a novel non-invasive marker predicting long-term outcomes in patients with non-ST elevation acute coronary syndrome" [1] with great interest. Both leukocytes and platelets have been reported to be involved in several cardiovascular (CV) diseases through inflammatory pathways.…”

“…The close relationship between inflammation, aggregation, and atherosclerosis progression has become a field of intensive research. The study by Dehghani et al [1] evaluated the predictive role of white blood cell count/mean platelet volume (WBC/MPV) ratio (WMR) in long-term outcomes of acute coronary syndrome (ACS) patients. However, we have some comments regarding the presented study.…”