Which variable is the strongest adjusted predictor of quality of life in caregivers of patients with dementia?

Abdollahpour, Ibrahim; Salimi, Yahya; Noroozıan, Maryam; Majdzadeh, Reza

doi:10.1111/psyg.12094

Cited by 34 publications

(34 citation statements)

References 28 publications

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“…These findings are consistent with previous research on quality of life in patients with dementia and other conditions. [36][37][38][39] However, it is important to note that the amount of variability in caregiver HRQOL explained by sociodemographic factors, caregiving time, perceived care burden, and dementia-related clinical factors across all the models is rather small. This implies that HRQOL ideally needs to be assessed by self-report rather than inferred from indirect data such as subjective caregiver burden.…”

Section: Discussionmentioning

confidence: 96%

Does health‐related quality of life in Asian informal caregivers differ between early‐onset dementia and late‐onset dementia?

et al. 2020

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Aim: Early-onset dementia (EOD) (defined as dementia onset before age 65) presents specific challenges and issues, adding to the negative impact of dementia on the health-related quality of life (HRQOL) of both patients and their caregivers. However, very few published studies have specifically compared the HRQOL of caregivers of people with EOD and late-onset dementia (LOD). This information is critical in allocating and prioritizing scarce health-care resources. We aimed to assess the HRQOL of primary informal caregivers of community-dwelling individuals with EOD in Singapore and compare it with that of caregivers of individuals with LOD. Methods: This was a cross-sectional study of consecutive patientcaregiver dyads from a tertiary dementia clinic. Results: No significant differences in disease severity were found between the 111 EOD and 235 LOD patient-caregiver dyads. The mean Mental Component Summary score of the 36-item Short-Form Health Survey version 2 was significantly worse in caregivers of EOD patients than in LOD caregivers (mean: 41.42 vs 45.12, P = 0.001), although the mean Physical Component Summary scores were comparable (49.71 vs 49.53, P = 0.934). However, the impact of dementia early onset on caregivers' mental health diminished immediately after adjustment for the disease severity indicators, of which the Neuropsychiatric Inventory Questionnaire distress score was the only significant clinical factor (regression coefficient β = −0.29, P < 0.001). The amount of variability in the HRQOL of the caregivers explained by patient and caregiver factors across all the models was rather small (adjusted R 2 = 19.3% for the Mental Composite Score, 5.2% for Physical Composite Score). Conclusion: Caregivers of EOD patients had worse mental health than LOD caregivers probably because individual with EOD have more behavioural disturbances. This reinforces the indispensable role of managing behavioural problems when caring for a family member with dementia, especially for EOD. HRQOL ideally needs to be assessed based on self-report rather than inferences from indirect data such as the subjective caregiver burden.

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Section: Discussionmentioning

confidence: 96%

Does health‐related quality of life in Asian informal caregivers differ between early‐onset dementia and late‐onset dementia?

et al. 2020

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“…Saeedfiroozabadi M 1,2 , Jalilian M 3 , Chenary R *3, 4 ( activities, stress management, spiritual growth, nutrition, health and interpersonal relationships responsibility. After data collection, the data entry was done using SPSS 21 statistical software and then analyzed through appropriate statistical tests of descriptive statistics, Analysis of Variance (ANOVA), Pearson Correlation Coefficient and Linear Regression.…”

Section: Analysis Of Health Promoting Behaviors Among Employees Of Ilmentioning

confidence: 99%

Analysis of Health Promoting Behaviors among Employees of Ilam University of Medical Sciences during 2014-15

Firoozabadi

Jalilian

Chenary

2018

sjimu

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“…Dementia and cognitive impairment are the major causes for the development of long-term impairment in activities of daily living [ 13 – 15 ] and are the main contributing factor to institutionalization in the elderly population [ 16 ], emphasizing the need for appropriate service and intervention programs. Dementia is also a burden for family care givers who often show high levels of psychological morbidity [ 17 ] and reduced quality of life [ 18 ]. Dementia patients have increased mortality compared to non-demented people [ 19 – 21 ].…”

Section: Introductionmentioning

confidence: 99%

Hearing Impairment Affects Dementia Incidence. An Analysis Based on Longitudinal Health Claims Data in Germany

Fritze

Teipel

Óvári³

et al. 2016

PLoS ONE

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Recent research has revealed an association between hearing impairment and dementia. The objective of this study is to determine the effect of hearing impairment on dementia incidence in a longitudinal study, and whether ear, nose, and throat (ENT) specialist care, care level, institutionalization, or depression mediates or moderates this pathway. The present study used a longitudinal sample of 154,783 persons aged 65 and older from claims data of the largest German health insurer; containing 14,602 incident dementia diagnoses between 2006 and 2010. Dementia and hearing impairment diagnoses were defined according to International Classification of Diseases, Tenth Revision, codes. We used a Kaplan Meier estimator and performed Cox proportional hazard models to explore the effect of hearing impairment on dementia incidence, controlling for ENT specialist care, care level, institutionalization, and depression. Gender, age, and comorbidities were controlled for as potential confounders. Patients with bilateral (HR = 1.43, p<0.001) and side-unspecified (HR = 1.20, p<0.001) hearing impairment had higher risks of dementia incidence than patients without hearing impairment. We found no significant effect for unilateral hearing impairment and other diseases of the ear. The effect of hearing impairment was only partly mediated through ENT specialist utilization. Significant interaction between hearing impairment and specialist care, care level, and institutionalization, respectively, indicated moderating effects. We discuss possible explanations for these effects. This study underlines the importance of the association between hearing impairment and dementia. Preserving hearing ability may maintain social participation and may reduce the burden associated with dementia. The particular impact of hearing aid use should be the subject of further investigations, as it offers potential intervention on the pathway to dementia.

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Which variable is the strongest adjusted predictor of quality of life in caregivers of patients with dementia?

Abstract: Caregiver burden was proposed as the strongest adjusted predictor for caregivers' poor QOL. Therefore, it seems that interventions to reduce caregiver burden can be effective in enhancing caregivers' QOL.

Cited by 34 publications

References 28 publications

Does health‐related quality of life in Asian informal caregivers differ between early‐onset dementia and late‐onset dementia?

Does health‐related quality of life in Asian informal caregivers differ between early‐onset dementia and late‐onset dementia?

Analysis of Health Promoting Behaviors among Employees of Ilam University of Medical Sciences during 2014-15

Hearing Impairment Affects Dementia Incidence. An Analysis Based on Longitudinal Health Claims Data in Germany

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