Which medical devices and/or local drug should be curatively used, as of 2012, for PU patients? How can granulation and epidermidalization be promoted? Developing French guidelines for clinical practice

Nicolas, B.; Moiziard, A.S.; Barrois, B.; Ribinik, P.; Colin, D.; Michel, Jean-Marc; Passadori, Y.

doi:10.1016/j.rehab.2012.08.005

Cited by 1 publication

(11 citation statements)

References 33 publications

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“…94,[97][98][99][101][102][103] Critical appraisal of SRs and meta-analyses Table 4 outlines the details of 18 reviews that have been published in the literature on the effect of EST on wound healing. 5,10,14,15,[104][105][106][107][108][109][110][111][112][113][114][115][116] Eight of the reviews completed at least some form of meta-analysis. 10,15,[104][105][106][107][108][109] Three other reports stated that although a meta-analysis was planned, none was done because of heterogeneity of included studies.…”

Section: Narrative Reviewsmentioning

confidence: 99%

“…10,15,[104][105][106][107][108][109] Three other reports stated that although a meta-analysis was planned, none was done because of heterogeneity of included studies. 14,112,113 The first SR published on this topic was produced by Gardner et al in 1999, and impressively, it also included a meta-analysis. 109 The results of eleven of the 18 included SRs favored the use of EST in the treatment of various types of chronic wou nds.…”

Section: Narrative Reviewsmentioning

confidence: 99%

“…In four reviews, the authors' recommendations suggested that there was no evidence to support routine clinical use of EST for wound therapy. 14,[112][113][114] Three other reports felt that research was inconclusive. 15,106,115 It is understandable with the variety of conclusions that clinicians become confused and feel that this area of research has conflicting results.…”

Section: Narrative Reviewsmentioning

confidence: 99%

“…[7][8][9][10][11][12][13][14][15] BPG panels with international and interprofessional representation have reviewed research related to a particular wound type and often assigned EST the highest level of research evidence and strongly support the use of EST in clinical practice. [7][8][9][10][11][12] Some BPGs have not recommended EST because of the conflicting results that have emerged from a plethora of recent systematic reviews (SRs).…”

Section: Introductionmentioning

confidence: 99%

“…[7][8][9][10][11][12] Some BPGs have not recommended EST because of the conflicting results that have emerged from a plethora of recent systematic reviews (SRs). [13][14][15][16] SRs and meta-analyses SRs and meta-analyses were introduced relatively recently as a novel research methodology that could help busy clinicians to stay abreast with current research trends. 17 An SR is a review of a clearly formulated question that uses systematic and explicit methods to identify, select, and critically appraise relevant research, and to collect and analyze data from the studies that are included in the review.…”

Section: Introductionmentioning

confidence: 99%

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Electrical stimulation therapy to promote healing of chronic wounds: a review of reviews

Houghton¹

2017

CWCMR

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Purpose:The overall objective of this study is to identify and appraise all of the existing clinical research literature that has evaluated the effect of electrical stimulation therapy (EST) on wound healing outcomes in adults with various types of chronic wounds. Methods: A systematic and comprehensive search of four electronic databases and gray literature was carried out, and references included in related review articles were checked. Prospective and controlled clinical trials, systematic reviews (SRs), and meta-analyses that assessed the effects of EST on wound healing outcomes were described and appraised. A total PRISMA score was assigned for each included SR based on criteria included in the assessment of multiple systematic reviews (AMSTAR) measurement tool. The percentage of available research that was identified in the SR was also calculated. Results: Sixty-two clinical research studies involving 2082 patients with pressure ulcers, venous leg ulcers, diabetic foot wounds, and arterial/ischemic wounds, and ulcers of mixed etiology were located. Thirty-three of the studies with 1370 patients compared wound size reduction after EST to a control group. Eighteen reviews that used a systematic approach to identify, select, and evaluate published studies on this topic have yielded conflicting results. Poorer quality SRs with a low total PRISMA score were more likely to yield negative or inconclusive findings. Most of these low-quality SRs had very vague research questions and included less than 50% of the available literature that was known to exist. Results from 22 well-designed randomized clinical trials and 10 high-quality SRs consistently support that EST can stimulate faster wound size reduction and/or produce a greater number of closed wounds compared to a group of similar patients receiving either standard wound care or sham EST. Conclusion: Pooled results from well-conducted SRs provide strong support for the use of EST on various types of chronic wounds and pressure ulcers in particular.

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