“…Prestroke variables were comorbidities noted in the medical history (hypertension, ischaemic heart disease, hypercholesterolaemia, diabetes mellitus, atrial fibrillation; all defined as present or absent). Stroke-related variables were stroke severity (National Institutes of Health Stroke Scale, NIHSS), 22 considered as a continuous variable and in subgroups (mild (0-7), moderate (8)(9)(10)(11)(12)(13)(14)(15)(16), severe (>16)), stroke type (ischaemic, haemorrhagic), Oxfordshire Stroke Classification 23 subgroups (total anterior circulation infarct (TACI), partial anterior circulation infarct (PACI), posterior circulation infarct (POCI), lacunar infarct (LACI), intracerebral haemorrhage (ICH)), ischaemic stroke location (large cortical, small cortical, hemispheric lacunar, brainstem, cerebellum, other, no infarct on imaging), stroke hemisphere (left, right, brainstem, not evident on imaging, unknown) and thrombolysis treatment with recombinant tissue plasminogen activator (yes, no). Stroke-related variables of stroke type, ischaemic stroke location and stroke hemisphere were reported based on information from routine neuroimaging (CT or MRI) performed at the local hospital.…”