Whey protein based electrosprayed nanospheres for encapsulation and controlled release of bioactive compounds from Tinospora cordifolia extract

Jain, Anshika; Dasgupta, Nandita; Ranjan, Shivendu; Singh, Vineeta; Singh, Hemant; Purohit, Shiv Dutt; Mishra, Narayan Chandra; Yadav, Narayan Prasad; Haque, Shafiul; Mishra, Bhartendu Nath; Samanta, Sujoy Kumar

doi:10.1016/j.ifset.2021.102671

Cited by 13 publications

(1 citation statement)

References 30 publications

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“…Encapsulations of bioactive components of Tinospora cordifolia extract viz . berberine, palmatine, and palmatoside into whey protein through electrospraying nanospheres with controlled delivery for anti-diabetic activity have been recently investigated by Jain et al (2021) . The synthesis of silver nanoparticles with the involvement of black cumin seed extract and its affectivity as an antidiabetic and anti-inflammatory agent has been investigated by Vijayakumar et al (2021a , b) .…”

Section: Application Of Nanoemulsionmentioning

confidence: 99%

Essential Oil Nanoemulsion as Eco-Friendly and Safe Preservative: Bioefficacy Against Microbial Food Deterioration and Toxin Secretion, Mode of Action, and Future Opportunities

et al. 2021

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Microbes are the biggest shareholder for the quantitative and qualitative deterioration of food commodities at different stages of production, transportation, and storage, along with the secretion of toxic secondary metabolites. Indiscriminate application of synthetic preservatives may develop resistance in microbial strains and associated complications in human health with broad-spectrum environmental non-sustainability. The application of essential oils (EOs) as a natural antimicrobial and their efficacy for the preservation of foods has been of present interest and growing consumer demand in the current generation. However, the loss in bioactivity of EOs from fluctuating environmental conditions is a major limitation during their practical application, which could be overcome by encapsulating them in a suitable biodegradable and biocompatible polymer matrix with enhancement to their efficacy and stability. Among different nanoencapsulated systems, nanoemulsions effectively contribute to the practical applications of EOs by expanding their dispersibility and foster their controlled delivery in food systems. In line with the above background, this review aims to present the practical application of nanoemulsions (a) by addressing their direct and indirect (EO nanoemulsion coating leading to active packaging) consistent support in a real food system, (b) biochemical actions related to antimicrobial mechanisms, (c) effectiveness of nanoemulsion as bio-nanosensor with large scale practical applicability, (d) critical evaluation of toxicity, safety, and regulatory issues, and (e) market demand of nanoemulsion in pharmaceuticals and nutraceuticals along with the current challenges and future opportunities.

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Section: Application Of Nanoemulsionmentioning

confidence: 99%