Whey protein and high-volume resistance training in postmenopausal women

Weisgarber, Krissy; Candow, Darren G.; Farthing, Jonathan P.

doi:10.1007/s12603-015-0454-7

Cited by 23 publications

(26 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Findings from previous studies have shown that both resistance training and protein supplementation are less effective in older adults than in younger adults; this is known as chronic blunting responsiveness in older people [ 31 , 32 , 33 ]. Furthermore, a recent study indicated that supplementation with protein or essential amino acids did not augment the effect of progressive resistance ET on body composition, muscle strength, size, or functional ability among older adults [ 34 ]. The blunting response could have caused the lack of difference in muscle mass and body composition among all the OVX groups with or without ISP supplementation or ET intervention.…”

Section: Discussionmentioning

confidence: 99%

Isolated Soy Protein Supplementation and Exercise Improve Fatigue-Related Biomarker Levels and Bone Strength in Ovariectomized Mice

et al. 2018

View full text Add to dashboard Cite

Isolated soy protein (ISP) is a well-known supplement and has been reported to improve health, exercise performance, body composition, and energy utilization. ISP exhibits multifunctional bioactivities and also contains branched-chain amino acids (BCAAs), which have been confirmed to positively affect body weight (BW) regulation and muscle protein synthesis. The combined effects of BCAA supplements and exercise in older postmenopausal women with osteoporosis, sarcopenia, and obesity have been inadequately investigated. Therefore, in this study, we evaluated the potential beneficial effects of soy protein supplementation and exercise training on postmenopausal mice. Forty mice (14 weeks old) with ovariectomy-induced osteosarcopenic obesity were divided into five groups (n = 8), namely sham ovariectomy (OVX, control), OVX, OVX with ISP supplementation (OVX+ISP), OVX with exercise training (ET, OVX+ET), and OVX with ISP and ET (OVX+ISP+ET). The mice received a vehicle or soy protein (3.8 g/kg BW) by oral gavage for four weeks, and the exercise performance (forelimb grip strength and exhaustive swimming time) was evaluated. In the biochemical profiles, we evaluated the serum glucose level and tissue damage markers, such as lactate, ammonia, glucose, blood urine nitrogen (BUN), and creatinine phosphate kinase (CPK). The body composition was determined by evaluating bone stiffness and muscle mass. All data were analyzed using one-way repeated measures analysis of variance. The physical performance of the OVX+ISP+ET group did not differ from that of the other groups. The OVX+ISP+ET group exhibited lower levels of serum lactate, ammonia, CPK, and BUN as well as economized glucose metabolism after an acute exercise challenge. The OVX+ISP+ET group also exhibited higher muscle mass and bone strength than the OVX group. Our study demonstrated that a combination of ISP supplementation and exercise reduced fatigue and improved bone function in OVX mice.

show abstract

Section: Discussionmentioning

confidence: 99%

Isolated Soy Protein Supplementation and Exercise Improve Fatigue-Related Biomarker Levels and Bone Strength in Ovariectomized Mice

et al. 2018

View full text Add to dashboard Cite

show abstract

“…The exercise load did not change during the 8 weeks of training and supplementation, as the purpose of the study was to overload the upper-and lower-body musculature by increasing the number of repetitions performed to volitional fatigue. Participants performed more sets for the lower-body because lower-body muscle groups exhibit a greater strength deficit (Candow and Chilibeck, 2005) and an attenuated muscle hypertrophic response to resistance training compared to upper-body muscle groups (Weisgarber et al, 2015). Training logs (Appendix D) were completed by each participant to ensure adherence and compliance to the study and to determine total training volume (weight x sets x repetitions).…”

Section: Supplementationmentioning

confidence: 99%

“…an attenuated muscle hypertrophic response to resistance training compared to upperbody muscle groups (Weisgarber et al, 2015). In addition, there is evidence that aging adults do not respond as well to the chest press exercise compared to the leg press exercise (Brown et al, 1990).…”

Section: Functionalitymentioning

confidence: 99%

Effects of high-velocity resistance training and creatine supplementation in untrained healthy aging males

Bernat

Candow

Gryzb

et al. 2019

Appl. Physiol. Nutr. Metab.

Self Cite

View full text Add to dashboard Cite

The purpose was to investigate the effects of high-velocity resistance training (HVRT) and creatine supplementation in untrained healthy aging males. Participants were randomized to supplement with creatine (0.1 g·kg−1·day−1 of creatine + 0.1 g·kg−1·day−1 of maltodextrin) or placebo (0.2 g·kg−1·day−1 of maltodextrin) during 8 weeks of HVRT. Prior to and following HVRT and supplementation, assessments were made for muscle strength, muscle thickness, peak torque, and physical performance. There was a significant increase over time for all measures of muscle strength (p < 0.001), muscle thickness (p < 0.001), and some measures of peak torque (knee flexion; 1.05 and 3.14 rad/s; p < 0.001) and physical performance (balance board time-to-completion; p = 0.017). There was a group × time interaction for leg press strength (p = 0.044) and total lower-body strength (leg press, knee flexion, knee extension combined; p = 0.039). The creatine group experienced greater gains in leg press and total lower-body strength compared with the placebo group, with no other differences. HVRT increases muscle strength, muscle thickness, and some measures of peak torque and physical performance in untrained healthy aging males. The addition of creatine supplementation to HVRT further augments the gains in leg press and total lower-body strength. Novelty High-velocity resistance training increases muscle mass and performance. Creatine supplementation increases lower-body muscle strength. High-velocity resistance training and creatine supplementation are safe interventions for aging adults.

show abstract

“…Nine RCTs further tested the effects of combination of different protein sources and RE in the elderly. The main findings of these studies are reported in Table 2 [52][53][54][55][56][57][58][59][60]. The overall results of these studies are concordant in providing evidence of the beneficial effects of RE and training, with some evidence encouraging a nutritional support with WP.…”

Section: Muscle Related Endpoints Among Healthy Subjects (40 Studies)mentioning

confidence: 67%

The Effects of Cow-Milk Protein Supplementation in Elderly Population: Systematic Review and Narrative Synthesis

et al. 2020

View full text Add to dashboard Cite

Background. To review currently available evidence on the effect of cow-milk proteins supplementation (CPS) on health in the elderly. Methods. Five electronic databases (Pubmed, Web of Science, Embase, Cochrane Library, ClinicalTrials.gov) were searched for studies about CPS among older people. All types of publications were included, with the exception of systematic reviews, meta-analyses, opinion letters, editorials, case reports, conference abstracts and comments. An additional search in Google Scholar and a manual review of the reference lists were performed. Results. Overall, 103 studies were included. Several studies explored the role of CPS in the preservation or improvement of muscle mass among healthy subjects (40 studies) and pre-frail, frail or sarcopenic patients (14), with evidence of beneficial effects. Other studies assessed the effect of CPS on bones (12), cardiovascular disease (8), inflamm-aging (7), chronic pulmonary disease (4), neurocognitive function (4), and vaccines (2), with weak evidence of positive effects. Seven studies in the field of protein metabolism investigated the role of CPS as an important contributor to nutritional needs. Other investigational areas are considered in the last five studies. Conclusions. The beneficial effects of CPS in achieving aged-related nutritional goals, in preserving muscle mass and in recovering after hospitalization may be particularly relevant in the elderly.

show abstract

Whey protein and high-volume resistance training in postmenopausal women

Abstract: High volume resistance training is effective for improving some indices of muscle mass and strength in postmenopausal women, but the strategic ingestion of whey protein during training sessions does not augment this response.

Cited by 23 publications

References 32 publications

Isolated Soy Protein Supplementation and Exercise Improve Fatigue-Related Biomarker Levels and Bone Strength in Ovariectomized Mice

Isolated Soy Protein Supplementation and Exercise Improve Fatigue-Related Biomarker Levels and Bone Strength in Ovariectomized Mice

Effects of high-velocity resistance training and creatine supplementation in untrained healthy aging males

The Effects of Cow-Milk Protein Supplementation in Elderly Population: Systematic Review and Narrative Synthesis

Contact Info

Product

Resources

About