Ultrasound examination of 897 patients with injuries and pathology of striated muscles was performed. Ultrasound criteria of muscle diseases and injuries were detected. The evaluation of diagnostic efficacy of ultrasound data relative to data of invasive methods (surgical interventions and diagnostic puncture) was performed. Ultrasound examination of striated muscles is showed to be a highly specific and sensitive method for diagnosis of traumatic muscle tissue lesions. Ultrasound allows to assess the hematoma volume, injury degree of muscle and diastasis length between muscle fibers; regeneration stage and developed scar of injured muscle as well as to detect cystic changes, ossificans myositis, hernia and tumor-like diseases.