When would we advocate a total thyroidectomy in cases of hypopharyngeal carcinoma?

Gad, Zeiad; Mohamed, Abdel-Maksoud; Fakhr, Ibrahim

doi:10.1016/j.jnci.2014.01.002

Cited by 2 publications

(3 citation statements)

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“…The researchers concluded that routine thyroid resection in larynx cancers should be limited to cases of subglottic or transglobic involvement (3). They recommended thyroidectomy in cases of bilateral tumors, high staging, postcricoid involvement, and clear radiological evidence (5) or in the event of muscle involvement or in case of subglottic involvement of more than 10 mm (7).…”

Section: Discussionmentioning

confidence: 99%

“…The rate of thyroid gland involvement in larynx and hypopharynx cancers has been reported from 5% to 30% in various studies (3)(4)(5)(6)(7)(8). There are no clear vascular and lymphatic linkages between the thyroid gland and larynx, and most researchers agree that thyroid involvement in the larynx and hypopharynx cancers could occur only through local invasion (5)(6)(7)(8)(9). The major risk factors for thyroid gland involvement in larynx cancers are laryngeal cartilage involvement, extensive subglottic, and transglottic involvement (5-7), but the degree of tumor differentiation effect on thyroid gland involvement and invasion is not clear.…”

Section: Introductionmentioning

confidence: 99%

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Thyroid Gland Involvement and the Efficiency of Thyroidectomy in Patients Having Larynx and Hypopharyngeal Cancers Treated with Surgery

et al. 2019

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Background: Thyroid gland involvement and invasion during larynx and hypopharynx cancers is rare, but due to the anatomical closeness of the thyroid gland and the larynx, it could occur through local invasion. Thyroidectomy is usually performed in patients with thyroid gland involvement having larynx and hypopharyngeal cancers. A lot of controversies exist regarding the thyroid gland involvement and efficiency of a different kind of thyroidectomy intraoperatively in these types of cancers. Objectives: Thus, elucidating the exact role of thyroidectomy, its efficiency, and parameters associated with thyroid gland involvement is critical in treating the patients with the larynx and hypopharyngeal cancers. Methods: In this retrospective study, the medical records of 117 patients admitted to Loghman Hakim Hospital from 2001 to 2015 with laryngeal and hypopharyngeal carcinoma, who underwent laryngectomy with or without thyroidectomy as a primary treatment of cancer, were evaluated. Several parameters, including gender, prevalence, location of the thyroid gland and lymph node involvement, the exact type of malignancy, differentiation stage of the tumor cells, the exact method of thyroidectomy, thyroid function, and its post-surgical cancer recurrence were assessed. Results: The prevalence of laryngeal cancers was significantly higher in males than females and most of the malignancies were squamous cell carcinoma (SCC). The location of the malignancy was mostly at supraglottis, glottis, transglottis, and subglottis, respectively. The rate of thyroid gland involvement was approximately 11.96%. Lobectomy was performed in 57.14 %, total thyroidectomy was performed in 35.71 %, and in 7.14% of the patients, and thyroidectomy was not performed. After the initial surgery, out of 11.96% of all patients with thyroid gland involvement, 28.5% had a recurrence of the thyroid gland. Only 21% of the patients with thyroid gland involvement had hypothyroidism after the surgery. Conclusions: The rate of thyroid gland involvement in the pathology report after surgery was approximately 3.41% of the thyroid gland involvement, which is low. We concluded that thyroidectomy is a very efficient way, but it should be limited to cases of subglottic or transglobic involvement or in cases of bilateral tumors, high staging, post-cricoid involvement, and clear radiological evidence or in the event of muscle involvement.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Thyroid Gland Involvement and the Efficiency of Thyroidectomy in Patients Having Larynx and Hypopharyngeal Cancers Treated with Surgery

et al. 2019

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“…Unlike other malignant epithelial tumors of the head and neck area, hypopharyngeal cancer has a very poor prognosis irrespective of the therapeutic regimen instituted; because of the late presentation, tendency to submucosal extension into the esophagus, lack of anatomical barriers of the hypopharyngeal wall and early metastases to regional lymphatic nodes of the neck, as well as a higher incidence of distant metastases3.An extended resection to achieve radicality is therefore mandatory and safe macroscopic margin is considered 4 .…”

Section: Introductionmentioning

confidence: 99%

Hypopharyngeal reconstruction using pectoralis major myocutaneous flap after total hypopharyngolaryngectomy

Hakeema¹,

Saleha²,

Gammal³

et al. 2018

Egyptian Journal of Neck Surgery and Otorhinolaryngology

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Introduction: Pharyngoeoesophageal defect after resection of hypopharyngeal carcinoma is usually reconstructed with gastric pull-up or free vascularized flap either jejunum or radial forearm. OBJECTIVE: The aim is to assess the use of pectoralis major myocutaneous flap (PMMCF) sutured directly to the prevertebral fascia for reconstruction of hypopharyngeal defect following total hypopharyngolaryngectomy. Material and Methods: Total hypopharyngolaryngectomy, total thyroidectomy, partial oesophagectomy and with or without neck dissections were performed for ten patients (seven females and three males) with hypopharyngeal cancer. The defects were reconstructed with PMMCF. The skin island was sutured to the prevertebral fascia. The main outcome measures included: durations of tube feeding, and hospital stay, character of diet and speech, persistent pharyngocutaneous fistula, recipient and donor site morbidity, tumor recurrence and mortality. Results: In seven out of ten patients, the

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When would we advocate a total thyroidectomy in cases of hypopharyngeal carcinoma?

Abstract: We would advocate a total thyroidectomy in cases of advanced stages of hypopharyngeal carcinoma, bilateral tumors, postcricoid carcinoma and in all patients with definite radiological evidence of thyroid gland invasion.

Cited by 2 publications

References 20 publications

Thyroid Gland Involvement and the Efficiency of Thyroidectomy in Patients Having Larynx and Hypopharyngeal Cancers Treated with Surgery

Thyroid Gland Involvement and the Efficiency of Thyroidectomy in Patients Having Larynx and Hypopharyngeal Cancers Treated with Surgery

Hypopharyngeal reconstruction using pectoralis major myocutaneous flap after total hypopharyngolaryngectomy

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