Background:By definition, anchor institutions have a long-term presence in their communities. Case studies of nonprofit anchor hospitals are common, but it is not clear whether for-profit hospitals are stable enough to fill this role. Our purpose is to determine whether for-profit hospitals are stable enough to fill the role of anchor institutions by strengthening their communities and elevating population health through a long-term presence stabilizing local economies. Methods: In this cross-sectional study, we analyzed national, secondary data between 2008 and 2017 compiled from the Dartmouth Atlas of Health Care, the American Hospital Association Annual Survey, and County Health Rankings. We used descriptive statistics to calculate the number of closures and mergers of hospitals of different ownership type, as well as the employment data. Using logistic regression, we assess whether for profit hospitals had higher odds of closing and merging, controlling for both organization and county characteristics.Results: For-profits are less stable than other hospitals, experiencing disproportionately more closures and mergers over time; a multivariate analysis found that this was a statistically significant difference. Additionally, for-profit hospitals have fewer full-time employees relative to their size than hospitals of other ownership types, as well as lower total payroll expenditures.Conclusions: Our findings suggest that for-profit hospitals are more efficient in terms of operating expenses, but this also may translate into a lower level of economic investment in the surrounding community. For-profit hospitals may also not have the stability required to serve as long-standing anchor institutions. Nonetheless, these organizations still have considerable potential due to their size, tax contributions, and impact on vulnerable communities where other types of hospitals have not been able to operate successfully. Identifying new policy incentives to engage these institutions may help improve population health in surrounding communities.