When is the Ideal Time to Perform Brain MRI in Patients with Transient Global Amnesia? Analysis of Case Series with Transient Global Amnesia from Previous Studies, based on Imaging Findings of Diffusion MRI According to Time Criteria

Theodorou, Georgios-Theofilos; Psoma, Elisavet; Mavropoulou, Xanthipi; Terzoudi, Aikaterini; Vadikolias, Κonstantinos

doi:10.31080/asne.2022.05.0468

Cited by 2 publications

(8 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The percentages of positive neuroimaging findings are highest between 36 to 48 h after the manifestation of the first clinical features of TGA. 9 Finally, we emphasize that the presence of diffusion imaging findings in the hippocampal formation is always reversible, as documented by the absence of permanent imaging findings in the T2 and FLAIR sequences. 10…”

Section: Electroencephalographic (Eeg) Findings In Patients With Tgamentioning

confidence: 75%

“…1 In follow-up neuroimaging, after a time frame of over 2 weeks, the high signal in DWI is not detected. 9…”

Section: Mri Findings In Patients With Tgamentioning

confidence: 99%

“…The percentages of positive neuroimaging findings are highest between 36 to 48 h after the manifestation of the first clinical features of TGA. 9…”

Section: Mri Findings In Patients With Tgamentioning

confidence: 99%

“…The probability of their detection increases after the first to third day, from the appearance of TGA. 9 These lesions are transient and are located in the CA-1 portion of the hippocampus. They are still detected for up to 7-10 days in DWI.…”

Section: Electroencephalographic (Eeg) Findings In Patients With Tgamentioning

confidence: 99%

“…1 In follow-up neuroimaging, after a time frame of over 2 weeks, the high signal in DWI is not detected. 9 The imaging finding of diffusion disturbance in the hippocampus is quite specific and sensitive to the diagnosis of TGA. The sensitivity of the MRI-DWI examination is stratified according to the time it is performed.…”

Section: Electroencephalographic (Eeg) Findings In Patients With Tgamentioning

confidence: 99%

See 4 more Smart Citations

Neuroimaging and Electroencephalographic Correlation in Patients with Transient Global Amnesia: Clinical Case Series

et al. 2022

Self Cite

View full text Add to dashboard Cite

Objective. To determine if there is any correlation between the electroencephalographic and neuroimaging findings in patients with Transient Global Amnesia (TGA). Methods: We retrospectively reviewed files of the First Department of Neurology of AHEPA University Hospital, including patients with a clinical diagnosis of TGA. Only patients who had the characteristic high signal in the temporal lobes in the DWI MRI and those who underwent electroencephalographic recording (EEG) were selected. Results: Out of 28 patients, 8 were selected. We found that 6 out of 8 patients (75%) who had imaging findings in DWI, in at least one medial temporal lobe, also had had intermittent slow theta waves on the electroencephalographic recording. Of these 6 patients, 3 (50%) had bilateral EEG findings, 2 patients (33,3%) only had findings on the left hemisphere and 1 (17%) had on the right hemisphere. 3 out of 6 patients (50%) had electroencephalographic dominance on the left, while 2 out of the 6 (33%) had on the right. In 2 patients with imaging findings in DWI no anomalies were demonstrated on EEG. In 3 out of 8 patients, both MRI and EEG findings correlated on the same side, while 1 patient had opposite findings, depending on which hemisphere the EEG anomalies dominated. Conclusions: There is no absolute matching between the DWI MRI and EEG findings in patients with the clinical diagnosis of TGA. However, there is some degree of correlation, when we focus on the focal dominance of the EEG anomalies, although not statistically significant.

show abstract

Section: Electroencephalographic (Eeg) Findings In Patients With Tgamentioning

confidence: 75%

“…1 In follow-up neuroimaging, after a time frame of over 2 weeks, the high signal in DWI is not detected. 9…”

Section: Mri Findings In Patients With Tgamentioning

confidence: 99%

“…The percentages of positive neuroimaging findings are highest between 36 to 48 h after the manifestation of the first clinical features of TGA. 9…”

Section: Mri Findings In Patients With Tgamentioning

confidence: 99%

Section: Electroencephalographic (Eeg) Findings In Patients With Tgamentioning

confidence: 99%

Section: Electroencephalographic (Eeg) Findings In Patients With Tgamentioning

confidence: 99%

See 3 more Smart Citations

Neuroimaging and Electroencephalographic Correlation in Patients with Transient Global Amnesia: Clinical Case Series

et al. 2022

Self Cite

View full text Add to dashboard Cite

show abstract

Guideline “Transient Global Amnesia (TGA)” of the German Society of Neurology (Deutsche Gesellschaft für Neurologie): S1-guideline

Sander¹,

Bartsch²,

Connolly³

et al. 2023

Neurol. Res. Pract.

View full text Add to dashboard Cite

Introduction In 2022 the DGN (Deutsche Gesellschaft für Neurologie) published an updated Transient Global Amnesia (TGA) guideline. TGA is characterized by a sudden onset of retrograde and anterograde amnesia for a period of one to a maximum of 24 h (with an average of 6 to 8 h). The incidence is estimated between 3 and 8 per 100,000 population/year. TGA is a disorder that occurs predominantly between 50 and 70 years. Recommendations The diagnosis of TGA should be made clinically. In case of an atypical clinical presentation or suspicion of a possible differential diagnosis, further diagnostics should be performed immediately. The detection of typical unilateral or bilateral punctate DWI/T2 lesions in the hippocampus (especially the CA1 region) in a proportion of patients proves TGA. The sensitivity of MRI is considered higher when performed between 24 and 72 h after onset. If additional DWI changes occur outside the hippocampus, a vascular etiology should be considered, and prompt sonographic and cardiac diagnostics should be performed EEG may help to differentiate TGA from rare amnestic epileptic attacks, especially in recurrent amnestic attacks. TGA in patients < 50 years of age is a rarity, therefore it is mandatory to rapidly search for other causes in particular in younger patients. The cause of TGA is still unknown. Numerous findings in recent years point to a multifactorial genesis. Because the pathomechanism of TGA is not yet clearly known, no evidence-based therapeutic or prophylactic recommendations can be made. Conclusions There is no evidence for chronic sequelae of TGA with respect to cerebral ischemia, chronic memory impairment, or the onset of dementia-related syndromes.

show abstract

When is the Ideal Time to Perform Brain MRI in Patients with Transient Global Amnesia? Analysis of Case Series with Transient Global Amnesia from Previous Studies, based on Imaging Findings of Diffusion MRI According to Time Criteria

Cited by 2 publications

References 0 publications

Neuroimaging and Electroencephalographic Correlation in Patients with Transient Global Amnesia: Clinical Case Series

Neuroimaging and Electroencephalographic Correlation in Patients with Transient Global Amnesia: Clinical Case Series

Guideline “Transient Global Amnesia (TGA)” of the German Society of Neurology (Deutsche Gesellschaft für Neurologie): S1-guideline

Contact Info

Product

Resources

About