When Is Low Potential Renal Acid Load (PRAL) Beneficial for Bone?

Krupp, Danika; Shi, Lijie

doi:10.1007/978-1-4471-2769-7_9

Cited by 2 publications

(1 citation statement)

References 38 publications

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“…In general Mg is at risk for being deficient in the diet [ 49 ]. Consumption of a rather plant-based fruit and vegetable-rich diet results in higher intakes of mineral cations, especially of K and Mg [ 50 ].…”

Section: Discussionmentioning

confidence: 99%

Urinary Mineral Concentrations in European Pre-Adolescent Children and Their Association with Calcaneal Bone Quantitative Ultrasound Measurements

Bussche

Herrmann

Henauw

et al. 2016

IJERPH

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This study investigates differences and associations between urinary mineral concentrations and calcaneal bone measures assessed by quantitative ultrasonography (QUS) in 4322 children (3.1–11.9 years, 50.6% boys) from seven European countries. Urinary mineral concentrations and calcaneal QUS parameters differed significantly across countries. Clustering revealed a lower stiffness index (SI) in children with low and medium urinary mineral concentrations, and a higher SI in children with high urinary mineral concentrations. Urinary sodium (uNa) was positively correlated with urinary calcium (uCa), and was positively associated with broadband ultrasound attenuation and SI after adjustment for age, sex and fat-free mass. Urinary potassium (uK) was negatively correlated with uCa but positively associated with speed of sound after adjustment. No association was found between uCa and QUS parameters after adjustment, but when additionally adjusting for uNa, uCa was negatively associated with SI. Our findings suggest that urinary mineral concentrations are associated with calcaneal QUS parameters and may therefore implicate bone properties. These findings should be confirmed in longitudinal studies that include the food intake and repeated measurement of urinary mineral concentrations to better estimate usual intake and minimize bias.

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Section: Discussionmentioning

confidence: 99%