When inordinate tissue growth is beneficial: Improving silk production by increasing silk gland size

Bellés, Xavier

doi:10.1038/cr.2011.68

Cited by 4 publications

(2 citation statements)

References 8 publications

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“…1-3). Correlation was found in the body weight, gland weight and protein concentration of the gland [20].…”

Section: Resultsmentioning

confidence: 83%

Untitled

2018

RJLBPCS

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Bombyx mori L. CSR2 X CSR4 is a bivoltine cross-breed that produces more amount of silk. The body weight and gland weight of the silkworms are correlated to quantitative and qualitative production of silk. In the present study the body weight the gland weight and quantitative estimation of silk gland protein were thoroughly studied by supplementation of vitamin C and E. Increment in the body weight, gland weight and silk gland protein concentration are observed.Vitamin C supplementation is found to yield better result in concentration of silk gland protein in comparison to vitamin E.

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“…1-3). Correlation was found in the body weight, gland weight and protein concentration of the gland [20].…”

Section: Resultsmentioning

confidence: 83%

Untitled

2018

RJLBPCS

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“…Silkworms are characterized by silk ejection and cocooning, and the growth and development of the silk gland, the only silk-producing organ of silkworms, is closely related to silk protein synthesis. Silk glands are larger in high silk-producing strains compared with low silk-producing strains [35]. Transgenic techniques have revealed that Ras1 or Yorkie overexpression can increase silk gland size and improve silk production [36,37].…”

Section: Discussionmentioning

confidence: 99%

CRISPR/Cas9-Mediated Editing of BmEcKL1 Gene Sequence Affected Silk Gland Development of Silkworms (Bombyx mori)

Li,

Lao,

Sun

et al. 2024

IJMS

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The silkworm (Bombyx mori) has served humankind through silk protein production. However, traditional sericulture and the silk industry have encountered considerable bottlenecks and must rely on major technological breakthroughs to keep up with the current rapid developments. The adoption of gene editing technology has nevertheless brought new hope to traditional sericulture and the silk industry. The long period and low efficiency of traditional genetic breeding methods to obtain high silk-yielding silkworm strains have hindered the development of the sericulture industry; the use of gene editing technology to specifically control the expression of genes related to silk gland development or silk protein synthesis is beneficial for obtaining silkworm strains with excellent traits. In this study, BmEcKL1 was specifically knocked out in the middle (MSGs) and posterior (PSGs) silk glands using CRISPR/Cas9 technology, and ΔBmEcKL1-MSG and ΔBmEcKL1-PSG strains with improved MSGs and PSGs and increased silk production were obtained. This work identifies and proves that BmEcKL1 directly or indirectly participates in silk gland development and silk protein synthesis, providing new perspectives for investigating silk gland development and silk protein synthesis mechanisms in silkworms, which is of great significance for selecting and breeding high silk-yielding silkworm varieties.

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Bmsage is involved in the determination of cell number in the silk gland of Bombyx mori

Hou

Sun

et al. 2019

Insect Biochemistry and Molecular Biology

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When inordinate tissue growth is beneficial: Improving silk production by increasing silk gland size

Cited by 4 publications

References 8 publications

Untitled

Untitled

CRISPR/Cas9-Mediated Editing of BmEcKL1 Gene Sequence Affected Silk Gland Development of Silkworms (Bombyx mori)

Bmsage is involved in the determination of cell number in the silk gland of Bombyx mori

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