This study utilized Multilevel Modeling Analyses to explore predictors of marital satisfaction and to explore how those predictors might moderate any negative impact of children. The Marriage and Relationship Questionnaire (MARQ), which demonstrates cultural and gender invariance, has been used to explore predictors of marital satisfaction in different cultures. In earlier research using MARQ datasets from the U.S.A., U.K., Turkey, Russia and China (3,000 couples), regression analyses identified 13 predictors explaining from 62% to 74% of the variance in marital satisfaction. The current research took the six most powerful predictors (sexual fulfillment, kind spouse, humorous spouse, dependable spouse, having the same outlook, and having a physically attractive spouse) and number of children, and subjected those variables to a Multilevel Modeling Analysis. Results are discussed on the level of the individual and the dyad by culture. Cultural similarities and differences emerged; unique cultural patterns are discussed. Across cultures, all predictors were associated with marital satisfaction. The negative impact of children did not appear in every culture with alpha set at .01. Moderation analysis results suggest that, depending on culture, the negative impact of children is moderated by maintaining sufficient levels of sexual satisfaction, kindness, humor and dependability after children arrive.