“…We have previously published short pieces on the continued impact of Tuskegee 12 and on the impact of health issues of American presidents. 13 This issue features a full-length essay by Dr. Danielle Fine and colleagues on the background of the opiate crisis, a topic that frequently appears in JGIM due to the magnitude of the national problem in opiate use disorder and overdose deaths. 14 We hope to publish scholarly articles that inform our understanding in a variety of domains: how systemic racism has pervaded medical institutions; the role of government in spaces of inquiry and sickness; how the pharmaceutical and device industries have shaped practice patterns; the influence of both famous and unsung individuals and organizations; how representations of healers, patients, and diseases affect public discourses and private decisions; and more.…”