When a picture is worth a thousand words: Molecular and elemental imaging applied to environmental analysis – A review

Study on Absorption, Distribution, Metabolism, and Excretion Properties of Novel Insecticidal GABA Receptor Antagonist, Pyraquinil, in Diamondback Moth Combining MALDI Mass Spectrometry Imaging and High-Resolution Mass Spectrometry

“…However, due to the homogenization and extraction process prior to LC−MS/MS analysis, there is a complete loss of the spatiotemporal information, especially for the analytes in small insects, whose organs or tissues are difficult to identify and separate by means of manual dissection. 14 Benefiting from the unique features of visualized, label-free and nonspecific detection, matrix-assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI) has become particularly attractive for gaining the spatiotemporal information of diverse molecular species in tissue sections, without destroying the target tissues. 15,16 Now, a MALDI-MSI technique is widely used for the location of endogenous compounds and exogenous compounds in various insect tissues, such as drosophila, 17−19 mosquito, 20 cockroach, 21 fire ant, 22 earthworm, 23 fluke, 24−26 and honeybee.…”

“…Liquid chromatography–tandem mass spectrometry (LC–MS/MS) is commonly used for ADME studies owing to its excellent sensitivity and high specificity. However, due to the homogenization and extraction process prior to LC–MS/MS analysis, there is a complete loss of the spatiotemporal information, especially for the analytes in small insects, whose organs or tissues are difficult to identify and separate by means of manual dissection . Benefiting from the unique features of visualized, label-free and nonspecific detection, matrix-assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI) has become particularly attractive for gaining the spatiotemporal information of diverse molecular species in tissue sections, without destroying the target tissues. , Now, a MALDI-MSI technique is widely used for the location of endogenous compounds and exogenous compounds in various insect tissues, such as drosophila, − mosquito, cockroach, fire ant, earthworm, fluke, − and honeybee. , Recently, our team have clarified the degradation and toxicity difference mechanism of the neonicotinoid pesticides in honeybees using MALDI-MSI. , Through these innovative applications, the use of MSI has opened new doors in toxicokinetic analysis of pesticides …”

Water Oxidation Performance Enhanced by Electrochemically Designed Vacancies on a Prussian Blue Catalyst

“…Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) − analysis was carried out as an attempt to obtain qualitative information about the Fe/C ratio and spatial distribution on the film and to confirm the vacancy formation (see Supporting Information for more details on the techniquesection 12). The results presented on Figures S19 and S20 indicate the distribution of Fe and C over the TPB and APB films, and they were then used to study and identify the presence of vacancies in the APB film.…”

Atomic spectrometry update: review of advances in the analysis of metals, chemicals and materials

“…A review with 185 references by Francischini and Arruda was entitled "when a picture is worth a thousand words: molecular and elemental imaging applied to environmental analysis: a review". 12 A useful table presented the advantages, disadvantages and resolution capabilities of: matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS), secondary ion mass spectrometry (SIMS), desorption electrospray ionization mass spectrometry (DESI-MS), Raman, LA-ICP-MS, LIBS and synchrotron XRF. Each of these techniques was also discussed in separate sections of the review giving a brief theory and applications.…”