What treatments are effective for common cold in adults and children?

Driel, Mieke van; Scheire, Sophie; Deckx, Laura; Gevaert, Philippe; Sutter, An De

doi:10.1136/bmj.k3786

Cited by 24 publications

(23 citation statements)

References 34 publications

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“…A reason may lay in the lack of high‐quality clinical trials for OTC medications, which can discourage the pharmaceutical staff. In OTC products for cough, common cold or headache, the overall evidence is mostly of low or very low quality despite numerous available trials . For other OTC medications, however, such as ulipristal acetate for emergency contraception, nicotine replacement for smoking cessation and intranasal corticosteroids for allergic rhinitis, high‐quality evidence exists .…”

Section: Discussionmentioning

confidence: 99%

The impact of evidence from clinical trials on counselling for over‐the‐counter drugs: A national survey of pharmaceutical staff in German pharmacies

et al. 2019

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What is known and objective: Evidence from clinical trials should form the foundation of healthcare advice. Comparatively little has been investigated about the implementation of evidence in over-the-counter (OTC) counselling in community pharmacies. The objective of this study was to explore the current impact of clinical trials on OTC counselling from the perspective of pharmaceutical staff. Methods: Pharmaceutical staff in German community pharmacies were invited to participate in a nationwide cross-sectional survey using SoSci Survey. Within the questionnaire, the following items were queried: (i) attitudes towards influencing factors on OTC drug recommendation, (ii) practical procedure of OTC drug recommendations, (iii) experiences and challenges in handling clinical trials, and (iv) current and desired continuing education on self-medication. Multiple logistic regression was employed to identify predictors for OTC recommendations based on clinical trials in routine. Results and discussion: In total, 1068 participants completed the survey. (i) Clinical trial data were rated as 'very important' for drug recommendations by 33% and as 'rather important' by 50%. (ii) 8% reported that they base their recommendations on clinical trial data 'in almost all consultations', 40% 'in most consultations'. (iii) 69% faced difficulties in including clinical trial data into their counselling. (iv) 7% read original clinical trials at least once a month. Predictors for routine OTC recommendations based on clinical trials were as follows: male gender, university degree, clinical trials considered to be important for recommendations, inclusion of clinical trials in counselling assessed as easy, higher frequency of reading specialized literature per year, increasing number of working pharmacists in the pharmacy, and more casual than regular customers in the pharmacy.What is new and conclusion: Most of the pharmaceutical staff recognize the importance of clinical studies for self-medication advice. Based on self-report, however, clinical trial data are not taken routinely into account in practice. Only a minor

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Section: Discussionmentioning

confidence: 99%

The impact of evidence from clinical trials on counselling for over‐the‐counter drugs: A national survey of pharmaceutical staff in German pharmacies

et al. 2019

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“…Primary care is the most efficient, equitable and effective place to deliver health care for most of the population, and is underpinned by a growing scientific knowledge base as research in and about general practice has evolved and grown over the past 50 years . Research in this setting is required as never before, with an ageing population, increasing rates of multimorbidity, and management continuing to move out of the hospital and into the community setting . There is no other academic specialty that will focus on generalist care in the community, and general practice is integral to research translation.…”

Section: What Would Health Care Look Like Without General Practice Rementioning

confidence: 99%

General practice research: an investment to improve the health of all Australians

Manski‐Nankervis

Sturgiss

Liaw

et al. 2020

Medical Journal of Australia

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“…There was little evidence to support the use of most OTC products, but decongestants or antihistamines emerged as "the best choice" for annoying nasal symptoms in adults, the researchers reported in BMJ. 1 They wrote that adults should be advised to use nasal decongestants for no more than 3 to 7 days, depending on the product, to minimize their risk of chronic nasal congestion (rhinitis medicamentosa). 1 Other adverse effects of decongestants include insomnia, drowsiness, and headache.…”

Section: Evaluating Treatment Choicesmentioning

confidence: 99%

“…1 They wrote that adults should be advised to use nasal decongestants for no more than 3 to 7 days, depending on the product, to minimize their risk of chronic nasal congestion (rhinitis medicamentosa). 1 Other adverse effects of decongestants include insomnia, drowsiness, and headache.…”

Section: Evaluating Treatment Choicesmentioning

confidence: 99%

“…Antibiotics, which are still unnecessarily prescribed for the common cold, according to CDC, have no effect on nasal symptoms. [1][2] Instead, antibiotics are associated with an increased risk of adverse effects when used for the common cold, which is a viral infection, van Driel and colleagues reported. Yet, antivirals are not recommended either because of a lack of evidence for their effectiveness.…”

Section: Evaluating Treatment Choicesmentioning

confidence: 99%

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