What to expect from paraneoplastic syndromes of the nervous system in uterine cancer: A review of the literature

Svarna, Anna; Liontos, Michalis; Reppas, Georgios; Fiste, Oraianthi; Andrikopoulou, Angeliki; Dimopoulos, Meletios A.; Zagouri, Flora

doi:10.1016/j.gore.2023.101136

Cited by 3 publications

(2 citation statements)

References 48 publications

(64 reference statements)

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“…Paraneoplastic syndromes of nervous system associated with EC are rare. Clinical manifestations include encephalitis or encephalomyelitis usually linked to autoantibodies such as anti-Hu, Ma2associated, anti-CRMP5, anti-Ri, anti-KLHL1 that are generally secreted by neuroendocrine tumors [12]. Thus, it can also reveal as a subacute sensory neuronopathy associated with anti-Hu or anti-collapsinresponsive mediator protein 5 (CRMP5) antibodies, or as sensory-motor neuropathy.…”

Section: Discussionmentioning

confidence: 99%

A Neurological Paraneoplastic Syndrome in a Patient Affected by Severe Obesity: A Case Report

Caldarelli,

Spuntarelli,

Mingrone

et al. 2024

SN Compr. Clin. Med.

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Introduction: Obese women experience a greater occurrence of tumors that impact the reproductive system, frequently leading to delayed diagnosis because of postponed access to medical care and unconventional manifestations.Case presentation: A 52-year-old woman was hospitalized due to an unexplained fever. After ruling out the typical reasons for fever, our patient experienced an episode of metrorrhagia she attributed to her regular menstrual cycle. Further assessments, including measurements of FSH and LH levels, as well as subsequent diagnostic imaging, revealed the existence of an abnormal growth mass affecting the uterus. Conclusion:The objective of our paper is to emphasize the signi cance of exploring paraneoplastic signs and symptoms in this kind of subjects, enabling prompt diagnosis and the subsequent establishment of an appropriate therapeutic approach.

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Section: Discussionmentioning

confidence: 99%

A Neurological Paraneoplastic Syndrome in a Patient Affected by Severe Obesity: A Case Report

Caldarelli,

Spuntarelli,

Mingrone

et al. 2024

SN Compr. Clin. Med.

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“…Paraneoplastic neurologic syndromes in uterine cancer patients are very rare and have a variety of clinical presentations, the most common being cerebral degeneration. However, other neurological syndromes present with various symptoms, leading to delayed diagnosis [1] . Rarer paraneoplastic neurological syndromes associated with uterine cancer are Guillain-Barré syndrome, encephalitis, encephalomyelitis, subacute sensory neuropathy, sensory-motor neuropathy and other neurological manifestations.…”

Section: Introductionmentioning

confidence: 99%

A rare case of paraneoplastic Guillain-Barré syndrome in a patient with endometrial cancer

Farook,

Priyankara,

Aluwihare

et al. 2023

European Journal of Case Reports in Internal Medicine

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Introduction: Guillain-Barré syndrome is an acute, inflammatory polyradiculoneuropathy of autoimmune aetiology. It is a rare disease seen in 1 in 100,000 person-years. Up to 20% of those affected develop severe disability; mortality in Guillain-Barré syndrome is 5%. Guillain-Barré, associated with many malignancies as a paraneoplastic phenomenon, has been reported – especially in haematological malignancies such as lymphoma and leukaemia. Solid tumours associated with paraneoplastic Guillain-Barré syndrome are breast and lung cancers. The association between paraneoplastic Guillain-Barré syndrome and gynaecological malignancies are rare, and only a handful of cases have been previously reported in gynaecological cancers. Case description: We discuss a 65-year-old Sri Lankan female patient diagnosed with metastatic endometrial carcinoma who presented with paraneoplastic Guillain-Barré syndrome. The patient was treated appropriately and eventually recovered from her condition. Conclusion: Paraneoplastic Guillain-Barré syndrome is a rare phenomenon that clinicians can easily miss, and it has rarely been described in gynaecological cancers. Our patient was diagnosed with this rare phenomenon. The timely recognition and prompt treatment of this potentially life-threatening condition with multiple complications is essential in managing patients with malignancies and neuropathy. Further studies on paraneoplastic Guillain-Barré syndrome are needed as cases may be underreported.

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A neurological paraneoplastic syndrome in a patient affected by severe obesity: a case report

Caldarelli,

SPUNTARELLI,

Mingrone

et al. 2024

Preprint

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Introduction: Obese women experience a greater occurrence of tumors that impact the reproductive system, frequently leading to delayed diagnosis because of postponed access to medical care and unconventional manifestations. Case presentation: A 52-year-old woman was hospitalized due to an unexplained fever. After ruling out the typical reasons for fever, our patient experienced an episode of metrorrhagia she attributed to her regular menstrual cycle. Further assessments, including measurements of FSH and LH levels, as well as subsequent diagnostic imaging, revealed the existence of an abnormal growth mass affecting the uterus. Conclusion: The objective of our paper is to emphasize the significance of exploring paraneoplastic signs and symptoms in this kind of subjects, enabling prompt diagnosis and the subsequent establishment of an appropriate therapeutic approach.

show abstract

What to expect from paraneoplastic syndromes of the nervous system in uterine cancer: A review of the literature

Cited by 3 publications

References 48 publications

A Neurological Paraneoplastic Syndrome in a Patient Affected by Severe Obesity: A Case Report

A Neurological Paraneoplastic Syndrome in a Patient Affected by Severe Obesity: A Case Report

A rare case of paraneoplastic Guillain-Barré syndrome in a patient with endometrial cancer

A neurological paraneoplastic syndrome in a patient affected by severe obesity: a case report

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