What threshold values of antral follicle count and serum AMH levels should be considered for oocyte cryopreservation afterin vitromaturation?

Abstract

Not applicable.

In vitro maturation of human immature oocytes for fertility preservation and research material

“…In recent years, patients with breast cancer, blood cancer, brain cancer, gynecological cancer etc. have been provided with FP . In particular, breast cancer is the most common cancer in women and one‐third of cases affect women of reproductive age.…”

“…If the patient has a partner, cryopreservation of the blastocysts is recommended after IVM and artificial fertilization, although cryopreservation of the oocytes or OTC is considered if there is no partner. In one study, 301 of 340 patients with cancer opted for oocyte cryopreservation after counseling, whereas cryopreservation of the blastocysts and OTC was chosen at a rate of 11 and 14%, respectively . Currently, cryopreservation of the oocytes is the most important procedure, especially in the context of FP for oncofertility.…”

“…It is also necessary to explain the possibility that cryopreserved oocytes might not be obtained, even if FP is performed . For example, it was reported that oocytes cannot be collected from 2.8% of patients with cancer and that the antral follicle count and anti‐Müllerian hormone levels are useful for predicting the number of cryopreserved oocytes after IVM . Furthermore, the rate of chromosomal abnormality is higher in blastocysts that are obtained from IVM than in blastocysts that are obtained from conventional ART .…”

“…have been provided with FP. 10,12,15,16 In particular, breast cancer is the most common cancer in women and one-third of cases affect women of reproductive age. Accordingly, breast cancer is the main target for FP.…”

“…As shown in Table 2, various oocyte collection methods have been reported, depending on the purpose of oocyte collection. In FP, transvaginal aspiration, 10,15,47 intraoperative aspiration from the ovaries, 39 and collection from resected ovarian tissue 12,16,19,20,[48][49][50][51] have been reported with the record of a needle gauge. In IVM for patients with PCOS, transvaginal aspiration is the common method.…”