What's going on in vaccine technology?

Russo, Silvia; Turin, Lauretta; Zanella, A.; Ponti, W.; Poli, G.

doi:10.1002/(sici)1098-1128(199705)17:3<277::aid-med3>3.0.co;2-v

Cited by 11 publications

(1 citation statement)

References 155 publications

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“…In the present antibiotic resistance era, one of the promising strategies to control bacterial diseases relies on the use of bacteriophages. Phage therapy, which has a long history, has been mostly neglected by the Western world but has re-gained interest as an alternative to conventional antimicrobics in recent decades, especially for diseases lacking vaccines [106].…”

Section: Discussionmentioning

confidence: 99%

Bacteriophage Therapy in Companion and Farm Animals

Bianchessi,

De Bernardi,

Vigorelli

et al. 2024

Antibiotics

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Bacteriophages, which are viruses with restricted tropism for bacteria, have been employed for over a century as antimicrobial agents; they have been largely abandoned in Western countries but are constantly used in Eastern European countries with the advent of antibiotics. In recent decades, the growing spread of multidrug-resistant bacteria, which pose a serious threat to worldwide public health, imposed an urgent demand for alternative therapeutic approaches to antibiotics in animal and human fields. Based on this requirement, numerous studies have been published on developing and testing bacteriophage-based therapy. Overall, the literature largely supports the potential of this perspective but also highlights the need for additional research as the current standards are inadequate to receive approval from regulatory authorities. This review aims to update and critically revise the current knowledge on the application of bacteriophages to treat bacterial-derived infectious diseases in animals in order to provide topical perspectives and innovative advances.

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Section: Discussionmentioning

confidence: 99%