What Prognostic Factors Are Important in Duodenal Adenocarcinoma?

Bakaeen, Faisal G.

doi:10.1001/archsurg.135.6.635

Cited by 226 publications

(248 citation statements)

References 20 publications

Supporting

Mentioning

229

Contrasting

Unclassified

Order By: Relevance

“…The median number of TLNs assessed (interquartile range [IQR]) according to disease stage was 1 (IQR, 0-7) for stage I, 4 (IQR, 0-9) for stage II, and 8 (IQR, 4-13) for stage III. In patients with stage II cancer who had at least 1 lymph node assessed, the median number of TLNs assessed (IQR) was 6 (IQR, [3][4][5][6][7][8][9][10][11][12]. The median number of TLNs accessed (IQR) in patients with stage II disease was lower in patients with duodenal cancers (median, 3; IQR, 0-9) than in patients with jejunal cancers (median, 5; IQR, 2-10; P ¼ .01) and patients with ileal cancers (median, 5; IQR, 2-12; P < .01).…”

Section: Clinicopathologic Characteristicsmentioning

confidence: 99%

Prognostic value of lymph node evaluation in small bowel adenocarcinoma

Overman

Wolff

et al. 2010

Cancer

104

View full text Add to dashboard Cite

BACKGROUND:The presence of distant metastases and the completeness of resection are important prognostic factors in patients with small bowel adenocarcinoma (SBA); however, the influence of lymph node metastasis on patient outcome has not been well characterized. The objective of the current study was to evaluate the impact of the number of positive and negative lymph nodes on survival after curative resection. METHODS: Patients who had SBA diagnosed between 1988 and 2005 were identified from the Surveillance, Epidemiology, and End Results (SEER) registry. Cox proportional hazards regression analyses were performed after adjusting for age, sex, race, tumor stage, tumor grade, and primary site. Five-year disease-specific survival (DSS) was determined, all patients were categorized according to the total lymph nodes (TLNs) assessed, and patients with stage III disease also were categorized according to the number of positive lymph nodes (PLNs) and the PLN-to-TLN ratio (the lymph node ratio [LNR]). RESULTS: In total, 1991 patients (n ¼ 1216 with stage I/II SBA and n ¼ 775 with stage III SBA) were analyzed. Survival depended on the TLNs assessed. The 5-year DSS rate for patients with stage II disease was associated with the TLNs assessed (44%, 69%, and 83% for 0 TLNs, 1-7 TLNs, and >7 TLNs, respectively). The 5-year DSS for patients with stage III disease was associated with the number of PLNs (58% and 37% for <3 PLNs and 3 PLNs, respectively). Among patients with stage III disease, the LNR was even more predictive of survival than stratification by the number of PLNs. CONCLUSIONS: Survival after surgical resection for stage I, II, and III SBA was associated with the TLNs assessed. Stratifying patients with stage III disease into those with <3 PLNs and 3 PLNs significantly improved prognostication. Cancer 2010;116:5374-82.

show abstract

Section: Clinicopathologic Characteristicsmentioning

confidence: 99%

Prognostic value of lymph node evaluation in small bowel adenocarcinoma

Overman

Wolff

et al. 2010

Cancer

104

View full text Add to dashboard Cite

show abstract

“…Although they are considered to be very rare, there are studies that have shown that primary duodenal tumors are found in 15-25 % of cases of malignant tumors of the small intestine [5][6][7]. In the study group, primary duodenal malignant tumors were found in a number of 25 cases representing 17 % of all malignancies studied; in terms of pathology were adenocarcinomas.…”

Section: Discussionmentioning

confidence: 82%

Malignant Duodenal Lesion - Duodenal Tumor Vs Pancreatic Tumor - Semiological Radioimaging Characteristics

Sălcianu¹,

Bratu²,

Popa³

et al. 2017

JGPLD

View full text Add to dashboard Cite

“…Presence of upper gastrointestinal obstruction with annular pancreas without obstructive jaundice in elderly patients should not distract from possible co-existing PDC. The diagnosis is currently based on a multi-modality approach with abdominal CT scan and upper gastrointestinal endoscopy and biopsy [24][25][26][27][28].…”

Section: Resultsmentioning

confidence: 99%

Duodenal Carcinoma in a Patient with an Annular Pancreas: Rarity Personified

Vibhute¹

2017

JLRDT

View full text Add to dashboard Cite

What Prognostic Factors Are Important in Duodenal Adenocarcinoma?

Cited by 226 publications

References 20 publications

Prognostic value of lymph node evaluation in small bowel adenocarcinoma

Prognostic value of lymph node evaluation in small bowel adenocarcinoma

Malignant Duodenal Lesion - Duodenal Tumor Vs Pancreatic Tumor - Semiological Radioimaging Characteristics

Duodenal Carcinoma in a Patient with an Annular Pancreas: Rarity Personified

Contact Info

Product

Resources

About