What Makes Clinical Research in Developing Countries Ethical? The Benchmarks of Ethical Research

The Art of Writing and Implementing Standard Operating Procedures (SOPs) for Laboratories in Low-Resource Settings: Review of Guidelines and Best Practices

“…Moreover, it is the ethical principle of “collaborative partnership” to engage local researchers and to share the responsibilities within a study [29]. SOPs should be developed on-site to produce best practices in accordance with the available resources [27].…”

Vulnerability of pregnant women in clinical research

“…However, her definition does not clarify what constitutes vulnerability in pregnant research participants. To determine when research participants are vulnerable, Hurst starts by assessing the set of research ethics principles as described by Emanuel and colleagues (among others social value, scientific validity and informed consent) and argues that if any of these principles is fragile or threatened, research participants may be vulnerable 38 39. However, if all acts that render a certain study unethical would also render a research participant as vulnerable, it would be too demanding and little specific in what constitutes an identifiably increased likelihood compared to ordinary research participants.…”

Appropriateness of no-fault compensation for research-related injuries from an African perspective: an appeal for action by African countries: Table 1

“…Just as the first principle of not attaching blame translates to no-fault compensation in modern research ethics discourse, the concept of contributory collective responsibility also finds some support in contemporary ethical guidelines for conduct of international research as outlined by Emanuel et al , where the authors advocate both for ‘…collaborative partnership between researchers and sponsors in developed countries and researchers, policy makers, and communities in developing countries’ and also for the research to be valuable to the society in which it is conducted 37. Thus, if these ethical principles by Emanuel et al are followed, only research that is beneficial to the community in which the research is conducted will be carried out, and it then follows that the burden of compensation for RRIs does not fall on sponsors alone but rather, the host communities and countries should also contribute since they are also beneficiaries of the research enterprise.…”