What is the true burden of diphtheria, tetanus, pertussis and poliovirus in children aged 3–18 years in Asia? A systematic literature review.

Abstract

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Seroepidemiology of pertussis in Huzhou: A population-based, cross-sectional study

“…The World Health Organization (WHO) estimated over 169,000 reported cases of pertussis worldwide in 2018, with the majority originating from developing countries. Current research indicates a sustained high level of infection in the population [ 2 – 4 ], and there is a consensus that the burden of pertussis may be seriously underestimated [ 5 ]. Pertussis continues to be a significant public health concern, with a noticeable increase in reported cases in China in recent years [ 6 ], The annual reported incidence has risen from 0.12 per 100,000 in 2009 to 2.15 per 100,000 in 2019 [ 7 ], accompanied by outbreaks [ 8 ].…”